糖尿病高危人群血脂异常患病率及相关危险因素分析

Risk Factors and Prevalence of Dyslipidemia at High Risk in Diabetes Patients

目的：探讨与分析糖尿病高危人群血脂异常患病率及相关危险因素。方法：选择2013年2月～2015年6月在我院进行诊治的糖尿病合并血脂异常患者72例作为观察组,同期按照1：1的比例选择单纯糖尿病患者72例作为对照组,对两组的一般资料、生活行为、疾病状况与血液检查指标进行分析。结果：单因素分析显示,体重指数、腰臀比、舒张压、代谢综合征史、家庭收入与血脂异常明显相关（P〈0.05）。多元线性方程分析结果显示腰臀比、体重指数与代谢综合征史为导致血脂异常的主要危险因素（P〈0.05）。Pearson直线相关分析结果显示腰臀比、体重指数与代谢综合征史与TG、TC、LDL-C呈正相关关系（P〈0.05）,而与HDL-C均呈负相关（P〈0.05）。结论：2型糖尿病患者多伴随有血脂异常,腰臀比、体重指数与代谢综合征史为导致血脂异常的主要危险因素,并且两者可互相影响,要积极进行饮食与运动干预。

Objective： To investigate and analyze high risk of risk factors and prevalence of dyslipidemia at high risk ofdiabetes patients.Methods：From February 2013 to June 2015,selected 72 type 2 diabetes combined dyslipidemia patients inour hospital for treatment as the observation group,atthe same period by the 1：1 ratio,selected 72 patients of type 2 diabetesas the control group,both groups were performed investigation and analysis of general information,life behavior,disease statusand blood test indicators.Results：Univariate analysis showed that body mass index（BMI）,waist-hip ratio（WHR）,diastolic bloodpressure,history of metabolic syndrome,family income were related to the dyslipidemia （P〈0.05）.Multiple linear equationsshowed that the WHR,BMI and history of metabolic syndrome were the major risk factors for dyslipidemia （P〈0.05）.Pearsonlinear correlation analysis show WHR,BMI and history of metabolic syndrome were positively correlated to the TG,TC,LDL-C（P〈0.05）,and were negatively correlated to the HDL-C （P〈0.05）.Conclusion：Type 2 diabetes patients are more accompanieddyslipidemia,the WHR,BMI and history of metabolic syndrome are the major risks factor for dyslipidemia,and the type 2 diabetesand dyslipidemia can influence each other,we should actively carry out diet and exercise intervention.