38例含铜宫内节育器过敏反应文献分析

Literature Analysis of 38 Cases of Allergic Reactions Induced by Copper Containing Intrauterine Devices

目的探讨含铜宫内节育器所致过敏反应的一般规律和特点,为临床诊断、鉴别和处理提供依据。方法计算机检索CNKI、维普、万方、等中文数据库,对有关宫内节育器的过敏反应个案文献报道进行整理和分析。结果含铜宫内节育器相关过敏反应一般发生在首次使用含铜宫内节育器的女性中,既往有过敏史者易发生,与宫内节育器铜表面积大小或形状无关。多发生在计生机构或妇保机构,临床表现多样,可累及多个系统-器官,并可出现生殖系统特有的症状。如果判断为过敏反应,仅需取出宫内节育器短时间内即可痊愈。结论临床医生在放置IUD前需仔细询问使用者过敏史,同时备好抢救药品,掌握处理过敏性休克的技术。此外,在诊疗时如遇到类似过敏症状尤其是久治不愈时,需考虑到IUD所致过敏可能。

Objective To explore the clinic features and regularity of allergic reactions caused by copper containing intrauterine devices（IUD）, so as to provide a reference for clinical diagnosis and treatment.MethodsAllergic reactions caused by IUD reported in CNKI, VIP, Wanfang databases were collected and analyzed statistically.Results Copper containing IUD related allergic reactions generally occurred in women who ifrst use it especially in those who have a history of allergy in clinics, but it was not related to the copper surface or the shape of IUD. The allergic reactions mostly occurred in maternity care or family planning institutions, and involved multiple organs and systems. The clinical manifestations were various. There were also some symptoms of the reproductive system speciifcally. If allergic reactions were diagnosed, to take out the IUD and all symptoms would disappear in a short time.ConclusionDoctors should be careful to ask the women about the history of allergy before placing IUD, and to prepare ifrst aid and to master the technology of treating acute allergy. In addition, if a similar allergic reaction was encountered in the clinic, the possibility for IUD allergic reaction should be considered.