灌服N-氨甲酰谷氨酸对哺乳山羊羔羊生长性能、血液参数及器官重的影响

Effects of Oral N-Carbamylglutamate Supplementation on Growth Performance,Blood Parameters and Organ Weight of Suckling Kidlets

本试验旨在研究1-41日龄哺乳山羊羔羊灌服N-氨甲酰谷氨酸（NCG）对其生长性能、血液参数及器官重的影响。选取1日龄体重[（3.1±0.3）kg]相近的哺乳山羊羔羊32只,随机分在2个组中（每组16只）,按每天分别灌服0（对照）、100 mg/kg BW的NCG。于羔羊41日龄时进行屠宰。结果表明,与对照组相比：1）灌服NCG显著提高了1-41日龄羔羊平均日增重,显著降低了腹泻率（P〈0.05）;2）灌服NCG显著提高了41日龄羔羊血浆中总蛋白和白蛋白含量（P〈0.05）,而显著降低了21和41日龄羔羊血浆氨和尿素氮含量（P〈0.05）;3）灌服NCG显著提高了21和41日龄羔羊血浆胰岛素、生长激素及一氧化氮含量（P〈0.05）;4）灌服NCG显著提高了41日龄羔羊血浆精氨酸、鸟氨酸和瓜氨酸含量（P〈0.05）。5）灌服NCG显著提高了羔羊脾脏、小肠及大肠相对重量（P〈0.05）。结果提示,灌服NCG促进哺乳山羊羔羊的生长发育及内源精氨酸合成。

This study was conducted to investigate the effects of oral N-carbamylglutamate（ NCG） supplementation on growth performance,blood parameters and organ weight of suckling kidlets from 1 to 41 days of age.Thirty two suckling kidlets with similar body weight [（ 3.1 ±0.3） kg]w ere randomly assigned to 2 groups（ 16 kidlets per group） at 1 day of age. Two groups of kidlets were orally administrated NCG at the dose of 0（ control） and 100 mg / kg BW per day,respectively. All kidlets were sacrificed at 41 days of age. The results showed that compared with control group： 1） oral administration of NCG significantly increased average daily gain and reduced diarrhea rate of sucking kidlets at 1 to 41 days of age（ P〈0.05）;2） oral administration of NCG significantly increased plasma total protein and albumin contents of 41-day-old suckling kidlets（ P〈0.05）,meanw hile,significantly decreased plasma ammonia and urea nitrogen contents of 21- and 41-day-old suckling kidlets（ P〈0.05）;3） oral administration of NCG significantly increased plasma growth hormone,insulin and nitric oxide contents of 21- and 41-day-old suckling kidlets（ P〈0.05）;4） oral administration of NCG significantly increased plasma arginine,citrulline and ornithine contents of 41-day-old suckling kidlets（ P〈0.05）;5） oral administration of NCG significantly increased the relative weight of spleen,large intestine and small intestine of suckling kidlets（ P〈0.05）. In conclusion,oral administration of NCG increases synthesis of arginine and improve growth performance of suckling kidlets.