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激素替代治疗对老年甲状腺功能减退患者认知功能的作用探讨 被引量:2

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摘要 目的探讨激素替代治疗对老年甲状腺功能减退患者认知功能的作用。方法 74例甲状腺功能减退的老年患者,均给予甲状腺激素替代治疗,比较治疗前后患者甲状腺激素水平变化以及认知功能改善情况。结果与治疗前相比,治疗后患者的简易智能精神状态量表(MMSE)评分及游离三碘甲腺原氨酸(FT3)、游离甲状腺素(FT4)明显升高,但促甲状腺激素(TSH)明显降低,差异均有统计学意义(P<0.05)。结论老年甲状腺功能减退采用激素替代治疗,可显著改善患者的临床症状,提高其认知功能,值得临床借鉴和积极推广。
作者 杨非柯 陈伟
出处 《中国实用医药》 2016年第13期197-198,共2页 China Practical Medicine
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  • 1汪艳芳,马书平,苏永,赵志刚.老年与中青年甲亢的临床特点对比及误诊分析[J].中国误诊学杂志,2004,4(3):412-413. 被引量:14
  • 2支文军.初诊甲亢患者45例血脂和载脂蛋白变化的临床观察[J].中国现代医药杂志,2007,9(2):112-113. 被引量:8
  • 3Samuels MH. Cognitive function in subclinical hypothyroidism. J Clin Endocrinol Metab ,2010,95:3611-3613.
  • 4Demartini B. Prevalence of depression in patients affected by subclinical hypothyroidism. Panminerva Med ,2010,52:277-282.
  • 5Parle J, Roberts L. A randomized controlled trial of the effect of thyroxine replacement on cognitive function in community-living elderly subjects with subclinical hypothyroidism:the Birmingham Elderly Thyroid study. J Clin Endocrinol Metab, 2010, 95: 3623-3632.
  • 6Ceresini G, Lauretani F. Thyroid function abnormalities and cognitive impairment in elderly people : results of the Invecchiare in Chianti study. J Clin Endocrinol Metab ,2009,57:89-93.
  • 7Jorde R, Waterloo K. Neuropsychological function and symptoms in subjects with subclinical hypothyroidism and the effect of thyroxine treatment. J Clin Endocrinol Metab,2006,91:145-153.
  • 8Wheeler SM, Willoughby KA, McAndrews MP. Hippocampal size and memory functioning in children and adolescents with congenital hypothyroidism. J Clin Endocrinol Metab,2011,22 : 123-126.
  • 9He XS, Ma N, Pan ZL. Functional magnetic resource imaging assessment of altered brain function in hypothyroidism during working memory processing. Eur J Endocrinol,2011,164 :951-959.
  • 10Fernandes RS, Alvarenga NB, Silva TI. Cognitive dysfunction in patients with subclinical hypothyroidism. Arq Bras Endocrinol Metabol,2011,55 :224-228.

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