年龄对胰十二指肠切除术影响性分析

The Impact of Analysis of Age for Pancreaticoduodenectomy

目的探讨年龄是否是影响胰十二指肠切除术独立危险因素。方法回顾性分析新疆医科大学第一附属医院2011年2月至2015年2月期间行胰十二指肠切除术患者的临床资料,按年龄<50岁、50岁≤年龄<60岁、60岁≤年龄<70岁、70岁≤年龄<75岁、75岁≤年龄<80岁和年龄≥80岁分为6组,对6组病例的并发症、术后住院时间、死亡率等数据进行统计分析。结果美国麻醉师协会(American Society of Anesthesiology,ASA)分级(P<0.001)、高血压(P<0.001)、冠心病(P=0.001)、糖尿病(P=0.002)、心衰(P=0.001)、呼吸衰竭(P=0.037)、术后住院时间(P=0.014)和胃排空延迟C级(P=0.006)各年龄组间比较差异具有统计学意义;而胰瘘(P=0.058)、术后出血(P=0.786)、死亡率(P=0.125)等并发症各年龄组间比较差异无统计学意义。结论年龄不是影响胰十二指肠切除术的独立危险因素,但应对术前伴随疾病进行严格评估。

Objective To investigate the age of patients can be the independence factor to affect the feasibility of pancreaticoduodenectomy. Methods The cases in the First Affiliated Hospital, Xinjiang Medical University from Feb. 2011 to Feb. 2015 were retrospectively analyzed, and divided into six groups according to age〈50, 50 ≤ age〈60,604 age〈 70, 70 ≤ age〈75,70 ≤ age〈80, ands〉 80 years old. The complications, hospitalization days, and mortality rates for six groups were analyzed. Results The differences in ASA classification （P〈0.001）, hypertension （P〈0.001）, coronary heart disease （P=0.001）, diabetes mellitus （P〈0.001）, heart failure （P=0.001 ）, respiratory failure （P=0.037）, postoperative hospitalization days （P=0.014）, and delayed gastric emptying grade C （P=0.006） had statistical significance, and pancreatic fistula （P= 0.058）, postoperative bleeding （P=0.786）, and mortality （P=0.125） of the different age groups had no significant difference. Condusion Age is not the independent risk factor to affect the feasibility of pancreaticoduodenectomy, but the strictly preoperative comorbidities assessment is necessary.