苯作业人群脂肪肝与性别和年龄的相关性研究

Correlation study of fatty liver and both age and gender in benzene exposed populations

目的探讨苯作业人群年龄、性别与脂肪肝的关系。方法以2 666例苯作业人群为研究对象进行肝脏超声检查。按照不同性别及年龄段分组,统计不同性别、年龄组中脂肪肝工人的比例。结果苯作业人群男女脂肪肝患病率均随年龄增长而呈增加的趋势。男性脂肪肝患病率≤30岁组为10.9%,31~40岁组为18.2%,41~50岁组为25.2%,51~60岁组为29.1%;女性4个年龄组脂肪肝患病率分别为6.9%、10.2%、17.8%、31.3%。50岁以前男性脂肪肝患病率为17.6%,女性为11.2%,男性明显高于女性（P〈0.01）;50岁以后男女脂肪肝患病率无明显差异（P〉0.05）。结论苯作业人群中性别、年龄均为脂肪肝患病的危险因素。

Objective To investigate the prevalence of fatty liver in benzene exposed populations with gender and age.Methods The liver ultrasound examination was performed in 2666 workers exposed to benzene.The examination population was divided into different groups according to different genders and ages.then,the prevalence of fatty liver was compared between the different groups.Results The prevalence of fatty liver disease in benzene exposed populations increased with age,the prevalence of fatty liver in the male groups≤30years old was 10.9%,18.2%in groups 31~40years old,25.2%in groups 41~50years old,29.1%in groups 51~60years old,and females 6.9%、10.2%、17.8%、31.3%among the four responding age groups.In the groups younger than 50 years old,the prevalence of fatty liver in the males was 17.6%and females 11.2%,the prevalence of fatty liver were significantly higher in male than that in female population in responding age group（P〈0.01）,but in population older than 50 years,there was no significant prevalence of fatty liver difference between men and women（P 〉0.05）.Conclusions Both age and gender in benzene exposed populations are risk factors for the prevalence of fatty liver.