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少量蛋白尿IgA肾病患者的临床与牛津病理分析 被引量:2

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摘要 目的:通过分析以少量蛋白尿(尿蛋白定量<1 g/24 h)和(或)血尿为主的Ig A肾病患者的临床及病理资料,探讨牛津分型与临床指标的相关性。方法:收集整理502例Ig A肾病患者的临床及病理资料,根据牛津病理分型提出的M、S、E、T 4项病理指标进行分组,分别与平均动脉压、血肌酐及24 h尿蛋白定量临床指标进行比较分析。结果:(1)牛津分型中,单项病理指标以M1多见,病理类型以M1、S1、E0、T0例数偏多;(2)M0/M1、E0/E1、T0/T1-2三项病理指标与临床指标具有相关性,差异具有统计学意义(P<0.01),S0/S1与临床指标无相关性,差异无统计学意义(P>0.05)。结论:以少量蛋白尿为主的Ig A肾病患者临床表现与牛津分型之间具有相关性,牛津分型可以有效指导临床。
出处 《中国中西医结合肾病杂志》 2016年第6期525-526,共2页 Chinese Journal of Integrated Traditional and Western Nephrology
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参考文献9

  • 1Damico G. Natural history of idiopathic IgA nephropathy:role of clinical ang histological prognostic factors. Am J Kidney Dis, 2000,36 (2) : 227 - 237.
  • 2Rai A, Nast C, Adler S, et al. Henoch - Schonleinpurpura nephri- tis. J Am SocNephrol, 1999,10(12) :2637 - 2644.
  • 3Working Group of the International IgA Nephropathy, Network and the Renal Pathology Society, Cattran D C, et al. The Oxford classification of IgA nephropathy: rationale, clinicopathological correlations, and classification. Kidney Int ,2009,76(5) :534 -545.
  • 4Lemley KV, Lafayette RA, Derby G, et al. Prediction of early pro- gression in recently diagnosed IgA nephropathy. Nephrol Dial - Transplant,2007,23 ( 1 ) :213 - 222.
  • 5师素芳,张宏.对于IgA肾病牛津病理分型验证现状的分析[J].中华肾脏病杂志,2012,28(3):167-169. 被引量:14
  • 6彭用华,苏颖,赵亚娟,林春妮,孙桂芳,李航,于阳,黄庆元,叶葳,李雪梅,李学旺.IgA肾病牛津分型在肾脏预后评价中的应用[J].中国医学科学院学报,2013,35(1):102-107. 被引量:15
  • 7张骥,林海霞,章建娜,吕吟秋,苏震,许菲菲.IgA肾病牛津分型在判断肾脏预后中的作用[J].中国中西医结合肾病杂志,2013,14(2):145-147. 被引量:5
  • 8Rafai A. IgA nephropathy:Immune mechanisms beyond IgA me- sangial deposition. Kidney Int,2007,72 (3) : 239 - 241.
  • 9Roufosse CA, Cook HT. Pathological predictors of prognosis in immunoglobulin A nephropathy: a review. Current opinion in nephrology and hypertension,2009,18 (3) :212 - 219.

二级参考文献37

  • 1Haas M. Histologic subclassification of IgA nephropathy: a clinicopathologic study of 244 cases. Am J Kidney Dis, 1997, 29: 829-842.
  • 2Lee SM, Rao VM, Franklin WA, et al. IgA nepbropatby: morphologic predictors of progressive renal disease. Hum Pathol, 1982, 13: 314-322.
  • 3Roberts IS, Cook HT, Troyanov S, et al. The Oxford classification of IgA nephropathy: pathology definitions, correlations, and reproducibility. Kidney Int, 2009, 76: 546- 556.
  • 4Cattran DC, Coppo R, Cook HT, et al. The Oxford classification of IgA nephropathy: rationale, clinicopathological correlations, and classification. Kidney Int, 2009, 76: 534-545.
  • 5Yamamoto R, Imai E. A novel classification for IgA nephropathy. Kidney Int, 2009, 76: 477-480, 2009.
  • 6Bleeker SE, Moll HA, Steyerberg EW, et al. External validation is necessary in prediction research: a clinical example. J Clin Epidemiol, 2003, 56: 826-832.
  • 7E1 KK, Hill GS, Karras A, et al. Focal segmental glomernlosclerosis plays a major role in the progression of IgA nephropathy. II. Light microscopic and clinical studies. Kidney Int, 2011, 79: 643-654.
  • 8Shi SF, Wang SX, Jiang L, et al. Pathologic predictors of renal outcome and therapeutic efficacy in IgA nephropathy: validation of the oxford classification. Clin J Am Soc Nephrol, 2011, 6: 2175-2184.
  • 9Edstrom HS, Soderberg MP, Berg UB. Predictors of outcome in paediatric IgA nephropathy with regard to clinical and histopathological variables (Oxford classification). Nephrol Dial Transplant, 2012, 27: 715-722.
  • 10Kang SH, Choi SR, Park HS, et al. The Oxford classification as a predictor of prognosis in patients with IgA nephropathy. Nephrol Dial Transplant, 2012, 27: 252-258.

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