慢性阻塞性肺疾病急性加重期合并深静脉血栓形成的相关因素分析

Analysis of Factors Related of Chronic Obstructive Pulmonary Disease with Acute Exacerbation Complicated with Deep Vein Thrombosis Merger

探讨慢性阻塞性肺疾病急性加重期患者发生深静脉血栓形成的相关因素。采用回顾性病例对照研究分析慢性阻塞性肺疾病急性加重期合并深静脉血栓形成患者21例（病例组）及同期不合并深静脉血栓形成的慢性阻塞性肺疾病急性加重期患者60例（对照组）的基本资料、实验室指标及临床特征。多因素Logistic回归分析显示：下肢不对称肿胀≥1cm、卧床时间≥5天、慢性阻塞性肺疾病GOLD分级Ⅲ级-Ⅳ级、D-二聚体≥500μg/L是慢性阻塞性肺疾病急性加重期合并深静脉血栓形成的危险因素（P〈0.05）。

To investigate the occurrence of deep vein thrombosis merger in AECOPD.AECOPD patients complicated with deep vein thrombosis of 21 cases as case group,the same period AECOPD without deep vein thrombosis patients of 60 cases in the control group.The case control study was carried out on the basic information,laboratory tests and clinical features of the patients in the two groups. Multivariate Logistic regression analysis showed：bed time ≥5 days,asymmetric lower limb swelling ≥1cm,D-dimer≥500μg/L,COPD GOLD grade Ⅲ-Ⅳ level were the risk factors for AECOPD complicated with deep vein thrombosis（P〈0.05）.With the above risk factors of AECOPD should be vigilant in clinical work.