放射治疗对鼻咽癌患者骨导听力的影响

Effects of Radiotherapy on Bone Conduction Hearing Thresholds in Nasopharyngeal Carcinoma

探讨放射治疗对鼻咽癌患者骨导听力的影响。收集2010年2月-2014年2月在笔者所在科室治疗且资料完整的34例鼻咽癌患者,分别记录患者放疗前、放疗后6个月及放疗后1年双耳0.5kHz、1kHz、2kHz、4kHz四个语言频率骨导听阈,并对记录的数据进行统计分析。患者双耳0.5kHz、1kHz、2kHz、4kHz四个语言频率骨导阈值放疗后6个月及1年均高于放疗前,且两两比较差异均有统计学意义（P〈0.05）。放射治疗可以使鼻咽癌患者骨导听力下降,对于鼻咽癌放疗患者应尽早积极防治,避免骨导听力损失。

To investigate radiation-induced hearing loss in nasopharyngeal carcinoma clinical data of patients with nasopharyngeal carcinoma treated by the authors from February 2010 to February 2014 were collected.Conventional pure tone audiometry test was conducted.Bone conduction thresholds were recorded for frequencies of 0.5kHz,1kHz,2kHz,and 4kHz to compare hearing before and at 6 months and 1year after radiotherapy.Thresholds were examined separately for each frequency.The bone conduction thresholds before radiotherapy was lower than those at 6 months and 1year after radiotherapy.Thresholds were statistically significant for each frequency（P〈0.05）.This study shows that the bone conduction threshold increases significantly in patients with nasopharyngeal carcinoma treated with radiotherapy.All measures for early prevention and treatment should be considered as early as possible in patients with nasopharyngeal carcinoma to prevent advance of bone conduction hearing loss.