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CarbAcineto NP试验检测产碳青霉烯酶鲍曼不动杆菌的研究

Application of CarbAcineto NP test for detection of carabapenemase-producing Acinetobacter baumannii
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摘要 鲍曼不动杆菌为医源性条件致病菌,在非发酵菌感染中仅次于假单胞菌[1]。近来产碳青霉烯酶鲍曼不动杆菌在全球范围内的报道呈上升趋势,且其编码碳青霉烯酶的基因主要存在于可移动的基因元件上,可在医院环境中快速播散。因此,产碳青霉烯酶鲍曼不动杆菌的快速识别成为控制医院感染的关键。Carba NP试验在肠杆菌科和铜绿假单胞菌碳青霉烯酶的检测中效果显著,但由于鲍曼不动杆菌产酶活性较弱,在一定情况下 Carba NP 试验容易出现假阴性结果[2]。Dortet等[3]提出采用CarbAcineto NP试验能很大程度上提高产碳青霉烯酶鲍曼不动杆菌的检出率。本研究旨在评估CarbAcineto NP试验检测产碳青霉烯酶鲍曼不动杆菌的效果。
出处 《国际流行病学传染病学杂志》 CAS 2016年第3期210-211,共2页 International Journal of Epidemiology and Infectious Disease
基金 河北省卫生厅重点科技研究计划(20150332)
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