摘要
人皮肤表皮干细胞是具有无限增殖潜能以及多向分化能力的专能干细胞,广泛存在于表皮基底层以及毛囊隆突部位。目前,表皮干细胞在分离、纯化、培养等领域都取得了一定进展。表皮干细胞的应用主要在皮肤创面的修复、组织工程皮肤的构建以及基因治疗等领域。本文从干细胞的来源、分离、纯化鉴定、培养与应用等方面进行综述。
Epidermal stem cells（ESCs） were specific stem cell, which have the potential of proliferation and multi-directional differentiation. Epidermal stem cell located in epidermal basal layer and the eminence of hair follicle. At present, researches of epidermal stem cells in isolation, purifying, culture have made great progress. It was mainly applied in skin wound healing, building of tissue-engineered skin and gene therapy. This article reviews epidermal stem cells about its cell source, isolation, purifying, identification, culture and application.
出处
《现代生物医学进展》
CAS
2016年第21期4185-4189,4200,共6页
Progress in Modern Biomedicine
基金
国家质检公益性行业科研专项项目(201310132
201410019)
关键词
表皮干细胞
分离
鉴定
培养
应用
Epidermal stem cells
Isolation
Identify
Culture
Application
