某院学龄前儿童腹泻诊治368例

Diagnosis and treatment of diarrhea in preschool children in a hospital

目的:了解浙江省长兴县人民医院学龄前儿童腹泻的患病情况,探讨重型腹泻发生的危险因素.方法:选取2014-01/2015-12于浙江省长兴县人民医院门诊或住院治疗的368例腹泻儿童为研究对象,根据Vesikari Scale评分分为重型组(≥11分,n=50)和轻型组(<11分,n=318),比较两组的性别、年龄、户籍、户口来源、住址、发病季节、发病至就诊的时间等基线资料及病毒感染状况,采用多因素Logistics回归分析筛选出患儿发生重型腹泻的影响因素.结果:无论是男性还是女性,两组的年龄分布比较,差异无统计学意义(P>0.05).重型组的农业户籍、外地户口、住在郊区、冬春季节发病、发病至就诊时间≤24 h、轮状病毒感染的比例显著高于轻型组,差异均有统计学意义(P<0.05).多因素Logistics回归分析表明农业户籍、冬春季节发病、发病至就诊时间≤24 h、轮状病毒感染是患者出现重度腹泻的独立危险因素(P<0.05).结论:学龄前儿童是重型腹泻的高发人群,尤其是对于农业户籍、冬春季节发病、发病至就诊时间≤24 h、轮状病毒感染者要给予针对性的防治.

AIM： To investigate the prevalence of diarrhea in preschool children for severe diarrhea. and explore risk factors METHODS： A total of 368 preschool children with diarrhea treated at our hospital between January 2014 and December 2015 were enrolled for the study and divided into a severe group （≥1l points, n = 50） and a mild group （〈11 points, n = 318） according to the Vesikari Scale. Gender, age, census register, household source, address, season, time from onset to see a doctor and virus infection were compared between the two groups. Multivariate logistics regression analysis was performed to screen out the factors related to severe diarrhea.RESULTS： There were no significant differences in age distribution between the two groups regardless of boys or girls （P 〉 0.05）. The rates of agricultural household, nonlocal registered permanent residence, living in the suburbs, winter and spring seasons, time from onset to see a doctor ≤24 h, and rotavirus infection in the severe group were significantly higher than those of the mild group （P 〈 0.05）. Multivariate logistics regression analysis showed that agricultural household, winter and spring seasons, time from onset to see a doctor ≤ 24 h, and rotavirus infection were independent risk factors for severe diarrhea （P 〈 0.05）.CONCLUSION： Preschool children is at high risk for severe diarrhea. Particular prevention and treatment should be given to cases with risk factors such as agricultural household, winter and spring seasons, time from onset to see a doctor ≤ 24 h, or rotavirus infection