霉酚酸酯治疗糖尿病肾病的研究进展

The progress in research of mycophenolate mofetil in treatment of diabetic kidney disease

糖尿病肾病是糖尿病代谢异常引起的肾脏疾病,是全身微血管病的一部分,也是许多发展中国家终末期肾病的常见病因。近些年来,伴随着各项医疗技术的发展,有效控制了许多疾病,但是糖尿病肾病这种疾病仍旧尚未得到有效治疗,与其相关的发病率和死亡率有逐年上升的趋势。目前,相关研究发现,新型免疫抑制剂霉酚酸酯对糖尿病肾病具有一定的治疗作用。本文就新型免疫抑制剂霉酚酸酯对糖尿病肾病治疗的研究进展作一综述。

Diabetic kidney disease（DKD）is a kidney disease caused by metabolic abnormalities, with is a part of systemic microangiopathy, and also the common causes for end stage renal disease（ESRD） in many developing countries. With the develop-ment of medical treatment technique, lots of diseases have been controlled effectively in recent years. However, no effective therapy modes have been created to DKD, which keeps unimproved death rate and increased attack rate year by year.At present, the curative effect of Mycophenolate mofetil（MMF）, a new type of immunosuppressant, on DKD has been reported by researchers. This paper reviews the progress in research of MMF in treatment of Diabetic kidney disease.