121例糖尿病患者神经电生理分析

Neural electrophysiological analysis of 121 patients with diabetes

目的探讨神经电生理指标在糖尿病患者中的变化及其临床意义。方法按病程(以10年分界)分组对121例糖尿病患者的神经电生理检测结果进行分析。结果病程≥10年组运动神经的正中神经、腓总神经和胫神经传导速度下降异常率增加(P<0.05),正中神经、尺神经潜伏期延长异常率高于<10年组(P<0.05);周围运动神经波幅下降异常率也增高,但差异无统计学意义(P>0.05)。病程≥10年组感觉神经的正中神经、尺神经和桡神经传导速度下降异常率增加(P<0.05);正中感觉神经波幅降低异常率增高(P<0.05)。结论对糖尿病患者定期进行神经电生理检查,有助于糖尿病周围神经病的早期发现、早期治疗。

Objective To explore the changes and clinical significances of neural electrophysiological parameters in patients with diabetes.Methods Changes of neural electrophysiological parameters were analyzed in 121 diabetic patients.According to the course of disease（by 10 years）,the electrophysiological indexes were analyzed.Results There was difference in the electrophysiological indexes of 121 patients with diabetes mellitus.In more than10 years group,thd decreased abnormal rates of conduction velocity in the median nerve,peroneal nerve and tibial nerve motor nerve were increased（P〈0.05）.The abnormal rates of latency in median nerve and ulnar nerve were higher than that in 10years group（P〈0.05）.The decreased abnormal rate of amplitude in peripheral motor nerve was also increased,but the difference was not statistically significant in two groups（P〈0.05）.In more than 10 years group,the conduction velocity decreased abnormal rates in sensory nerve median nerve,ulnar nerve and radial nerve were increased（P〈0.05）.The decreased and the abnormal rate of amplitude in median sensory nerve was increased（P〈0.05）.Conclusion The regular nerve electrophysiological examination in patients with diabetes will be helpful for early detection,early diagnosis and earlytreatment of diabetic peripheral neuropathy.