Endogenous DNA Damage and Repair Enzymes—A short summary of the scientific achievements of Tomas Lindahl,Nobel Laureate in Chemistry 2015 被引量：2

Endogenous DNA Damage and Repair Enzymes—A short summary of the scientific achievements of Tomas Lindahl,Nobel Laureate in Chemistry 2015

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摘要 Tomas Lindahl completed his medical studies at Karolinska Institute in 1970.Yet,his work has always been dedicated to unraveling fundamental mechanisms of DNA decay and DNA repair.His research is characterized with groundbreaking discoveries on the instability of our genome,the identification of novel DNA repair activities,the characterization of DNA repair pathways,and the association to diseases,throughout his 40 years of scientific career. Tomas Lindahl completed his medical studies at Karolinska Institute in 1970.Yet,his work has always been dedicated to unraveling fundamental mechanisms of DNA decay and DNA repair.His research is characterized with groundbreaking discoveries on the instability of our genome,the identification of novel DNA repair activities,the characterization of DNA repair pathways,and the association to diseases,throughout his 40 years of scientific career.

作者 Arne Klungland Yun-Gui Yang

机构地区 Department of Microbiology Department of Molecular Medicine CAS Key Laboratory of Genomic and Precision Medicine

出处《Genomics, Proteomics & Bioinformatics》 SCIE CAS CSCD 2016年第3期122-125,共4页 基因组蛋白质组与生物信息学报（英文版）

关键词 DNA repair completed career instability decay dedicated summary Clare breaking DNA repair completed career instability decay dedicated summary Clare breaking

分类号 R346 [医药卫生—基础医学]

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7Lindahl T. An N-glycosidase from Escherichia coil that releases free uracil from DNA containing deaminated cytosine residues. Proc Natl Acad Sci U S A 1974;71:3649-53.
8Chetsanga C J, Lindahl T. Release of 7-methylguanine residues whose imidazole rings have been opened from damaged DNA by a DNA glycosylase from Escherichia coli. Nucleic Acids Res 1979;6:3673 84.
9Roldfin-Arjona T, Wei YF, Carter KC, Klungland A, Anselmino C, Wang RP. Molecular cloning and functional expression of a human eDNA encoding the antimutator enzyme 8-hydroxygua- nine-DNA glycosylase. Proc Natl Acad Sci U S A 1997;94: 8016-20.
10Dianov G, Price A, Lindahl T. Generation of single-nucleotide repair patches following excision of uracil residues from DNA. Mol Cell Biol 1992;12:1605-12.

引证文献2

1Jiadong Wang,Tomas Lindahl.Maintenance of Genome Stability[J].Genomics, Proteomics & Bioinformatics,2016,14(3):119-121.
2Shanshan Xie,Yuxia Jiao.That’s A Scientist Should Do——A Dialog with Tomas Lindahl[J].Genomics, Proteomics & Bioinformatics,2019,17(3):223-225.

1Shuangli Mi,Arne Klungland,Yun-Gui Yang.Base-excision repair and beyond—A short summary attributed to scientific achievements of Tomas Lindahl, Nobel Prize Laureate in Chemistry 2015[J].Science China(Life Sciences),2016,59(1):89-92.
2Yijing Su Guo-li Ming Hongjun Song.DNA damage and repair regulate neuronal gene expression[J].Cell Research,2015,25(9):993-994.
3Guo-Min Li.Celebrating the work of Nobel Laureate Paul Modrich[J].Science China(Life Sciences),2016,59(1):93-96.
4Recent CAS Achievements in Life Sciences[J].Bulletin of the Chinese Academy of Sciences,2003,17(1):52-62.
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7Hailing Shi,Xiao Wang,Zhike Lu,Boxuan S Zhao,Honghui Ma,Phillip J HSU,Chang Liu,Chuan He.YTHDF3 facilitates translation and decay of N6-methyladenosine-modified RNA[J].Cell Research,2017,27(3):315-328. 被引量：203
8Ning Wang,Rongliang Xue,Fengzhen Yao,Jiaxuan He,Jianrui Lu,Pengbo Zhang,Gang Wu.Neuronal effects of SP600125 pretreatment in a rat model of cerebral ischemia/reperfusion injury Inhibited down-regulation of DNA repair protein[J].Neural Regeneration Research,2009,4(12):1055-1061. 被引量：1
9Kaiying Cheng,Xin Xu,Ye Zhao,Liangyan Wang,Guangzhi Xu,Yuejin Hua.The key residue for SSB-RecO interaction is dispensable for Deinococcus radiodurans DNA repair in vivo[J].Acta Biochimica et Biophysica Sinica,2014,46(5):368-376. 被引量：1
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Endogenous DNA Damage and Repair Enzymes—A short summary of the scientific achievements of Tomas Lindahl,Nobel Laureate in Chemistry 2015 被引量：2

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