通脉复律汤治疗冠心病缓慢性心律失常患者110例的临床效果

Randomized controlled clinical observation of Tongmaifulv Decoction in the treatment of bradyarrhythmia in coronary heart disease

目的临床观察自拟通脉复律汤治疗冠心病缓慢性心律失常患者中医辨证属痰瘀互阻证的临床疗效。方法将2013年6月～2015年12月在北京市鼓楼中医院门诊就诊患者中诊断为冠心病缓慢性心律失常属痰瘀互阻证的患者110例,随机分为两组。治疗组55例在规范西医治疗同时口服通脉复律汤,对照组55例在规范西医治疗同时合用中成药利脑心片,在治疗16周后比较两组患者的心率变化、心悸、胸闷等主要症状及心电图变化。结果治疗组使用口服通脉复律汤治疗,患者临床症状、心室率的改善情况与对照组比较,差异有统计学意义（P〈0.05）。两组患者心电图缺血性ST-T改变均有改善,但两组比较差异无统计学意义（P〉0.05）。结论通脉复律汤治疗冠心病缓慢性心律失常有较好的疗效,优于使用西药合用中成药治疗。

Objective To observe the clinical efficacy of Tongmaifulv Decoction on bradyarrhythmia patients with phlegm and blood stasis syndrome in coronary heart disease. Methods 110 cases of bradyarrhythmia patients with phlegm and blood stasis syndrome in coronary heart disease in the Gulou Hospital of Traditional Chinese Medicine of Beijing from June 2013 to December 2015 were randomly divided into treatment group and control group. Besides using standardized western medicine treatment in both groups, 55 cases in the treatment group were given Tongmaifulv Decoction while Linaoxin pills were applied in the control group. After 16 weeks of treatment, the changes of ventricular rate, electrocardiogram, and major symptoms such as chest distress and palpitation were compared between the two groups. Results The improvement of clinical symptoms and ventricular rate in the treatment group was better than that of the control group, with statistic difference（P〈 0.05）. The ischemic changes in electrocardiogram were improved in both groups, without statistical difference（P〉0.05）. Conclusion Tongmaifulv Decoction showes good effect in the treatment of bradyarrhythmia in coronary heart disease and has advantages over some Chinese patent medicine.