知母水层化学成分研究

Chemical Constituents in Water Fraction from Anemarrhena Asphodeloides Bge

目的：研究知母水层的化学成分。方法：利用大孔吸附树脂、反相ODS柱色谱结合高效液相技术对知母水层进行分离纯化,并根据波谱数据鉴定化合物的结构。结果：从知母水层中分离出5个化合物,分别鉴定为L-脯氨酸（1）,L-缬氨酸（2）,亮氨酸（3）,异亮氨酸（4）,色氨酸（5）。结论：化合物1~4为首次从百合科中分离得到,化合物5为首次从知母属中分离得到。

Objective： To investigate the chemical constituents of water fraction from Anemarrhena asphodeloides Bge. Methods： The compounds were separated re raphies as well as high performance liquid c spectral data. Results ： Five compounds were isolated from the rhizomes of Anemarrhena asphodeloides Bge. They were identified as L - proline （ 1 ）, L - valine （2）, leucine （3）, isoleucine （4） and tryptophan （ 5 ）. Conclusion ： Compounds 1 -4 are isolated from Liliaceae for the first time, and the compound 5 is firstly isolated from Anemarrhena Bge.