孙氏腹针对中风恢复期患者CD62p表达及下肢运动功能评分的影响

Effect of Sun's Abdominal Acupoints on the Expression of CD62p and Recovery of Stroke Reconvalescent Lower Limb Disorder

目的:观察孙氏腹针对中风恢复期患者CD62p表达及下肢运动功能评分的影响。方法:将60名患者随机分为对照组及腹针组,疗程均为2周。应用流式细胞仪技术检测治疗前、后两组患者静脉血中CD62p含量的变化,并选择健康志愿者30名测定参考值。选用简化的下肢运动功能Fugl-Meyer评分,评估孙氏腹针治疗下肢功能障碍的效果。结果:治疗前后两组患者CD62p水平均高于健康组(P<0.01);两组治疗后CD62p水平较治疗前均明显降低(P<0.05),腹针组CD62p水平降低更为显著;与治疗前比较,两组评分差异有统计学意义(P<0.05),而腹针组评分高于对照组(P<0.05),腹针组临床症状改善更为明显。结论:孙氏腹针结合体针对中风恢复期患者下肢功能障碍有更好的改善,降低CD62p表达水平,尚需进一步深入研究。

Objective：To observe the effect of Sun＇ s abdominal acupoints on the expression of P selectin（CD62p） and recovery of stroke reconvalescent lower limb disorder. Methods： A total of 60 patients with lower limb disorder of stroke reconvalescent were randomly divided into a control group and an abdominal acupoint group, and the treatment course was for 2 weeks. The expression of CD62p was detected by flow cytometry pretherapy and post - treatment. Meanwhile, select 30 healthy volunteers as reference value. Evaluate the effect of recovery of stroke reconvalescents＇ lower limb function with Sun＇ s abdomen acupoints by simple score of the lower limb motor function. Results： The levels of CD62p in two groups were significantly higher than health group （P 〈 0.01 ）. The levels of post - treatment of CD62p in two groups were obviously lower than those before the use of therapy（ P 〈 0.05 ）, especially in abdominal acupoint group. Compared with pretherapy, there was significant differences of FMA scores in two groups （ P 〈 0.05 ）. The score of abdominal acupoint group was higher than that in the control group and it had a significant difference （P 〈0.01 ）.Compared with the control group, the improvement of clinical symptom in abdominal acupoint group was more obvious （ P 〈 0.05 ）. Conclusion- Sun＇ s abdominal acupoints combined with body acupuncture can improve the stroke reconvalescent＇ s lower limb disorder, with a depressant effect on the expression of CD62p, which needs a further research.