粤东地区农村2型糖尿病患者用药差异与糖尿病控制水平间的关系

Relationship between Medication Discrepancies and Diabetes Control in Patients with Type 2 Diabetes Mellitus in Rural of Eastern Guangdong Province

目的调查粤东地区农村2型糖尿病（T2DM）患者用药情况,分析患者用药差异与糖尿病控制水平间的关系,为患者用药管理提供参考。方法选取2014-06~2015-06到我院内分泌科门诊就诊的2型糖尿病患者共463例,采用修订的用药差异评估工具（MDT）对就诊患者进行调查,并记录患者空腹血糖和糖化血红蛋白值。结果调查的2型糖尿病患者空腹血糖（FPG）达标率为26.13%,糖化血红蛋白（Hb A1c）达标率为25.92%。181例（39.09%）患者能够描述其服用降糖药的名称和用法用量,FPG和Hb A1c的达标率分别为27.62%和29.28%;187例（40.39%）患者仅能描述其服用降糖药的名称,FPG和Hb A1c的达标率分别为31.55%和26.74%;95例（20.52%）患者的用药名称和用法用量均不能描述,其FPG和Hb A1c的达标率分别为12.63%和17.89%,与前2组相比,药品名称和用法用量均不能描述的患者的糖尿病控制水平明显降低（P〈0.05）。结论粤东地区农村2型糖尿病患者的空腹血糖和糖化血红蛋白达标率均较低,患者对所用降糖药物的掌握程度可显著影响糖尿病控制水平。

OBJECTIVE To survey the use of medicine in patients with type 2 diabetes mellitus（ T2DM） in rural of eastern Guangdong province,analyze the relationship between medication discrepancies and diabetes control,so as to provide reference of medication management for the patients. METHODS A total of 463 patients with T2 DM were selected from endocrine clinic of the hospital between June 2014 and June 2015. The patients were investigated by using modified medication discrepancy tool（ MDT）,and the values of fasting plasma glucose（ FPG） and glycosylated hemoglobin（ Hb A1c） were recorded. RESULTS The total compliance rates of FPG and Hb A1 c were 26.13% and 25.92% respectively; 181（ 39.09%） patients could provide the name,usage and dosage of antidiabetic drugs they took,the compliance rates were 27.62% and 29.28% respectively; 187（ 40.39%） patients could only name the medications,the compliance rates were 31. 55% and 26. 74% respectively; 95（ 20. 52%） patients were unable to name any of their medications,the compliance rates were 12. 63% and 17. 89% respectively,which were both significantly lower than the 2 groups of patients mentioned above. CONCLUSION The rates of controlled FPG and Hb A1 c were both unsatisfied in patients with T2 DM in rural of eastern Guangdong province,which may affected by the knowledge of antidiabetic medications the patients can master.