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老年冠心病患者血氧化型低密度脂蛋白改变及与促炎因子的相关性 被引量:8

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摘要 目的分析老年冠心病(CAD)患者外周血氧化型低密度脂蛋白(OX-LDL)及抗体的改变及与促炎因子的相关性。方法 CAD患者46例为观察组,老年健康体检者35例作为对照组,观察两组血脂水平、外周血细胞因子水平。结果观察组外周血OX-LDL及抗体水平显著高于对照组(P<0.001);观察组外周血肿瘤坏死因子(TNF)-α水平显著高于对照组(P=0.002)。Pearson相关性分析显示观察组外周血OX-LDL水平与OX-LDL抗体呈现显著正相关(r=0.630,P<0.001),同时OX-LDL水平与TNF-α水平呈现显著正相关(r=0.747,P<0.001)。结论 OX-LDL及其抗体在CAD患者外周的中表达升高,且与促炎因子TNF-α正相关,OX-LDL可用于CAD辅助诊断。
出处 《中国老年学杂志》 CAS CSCD 北大核心 2016年第13期3164-3165,共2页 Chinese Journal of Gerontology
基金 唐山市科技局资助项目(09130208b)
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参考文献9

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