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颈动脉内中膜厚度及斑块形成与冠状动脉病变的相关性 被引量:11

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摘要 目的探讨颈动脉内中膜厚度(IMT)增厚及斑块形成与冠状动脉病变的相关性。方法选取2012~2015年就诊于该院心内科160例均行颈动脉超声及冠脉造影检查的患者,其中男101例,女59例,平均年龄(58±19)岁。颈动脉IMT增厚超过1.0 mm和(或)出现斑块定义为阳性,冠状动脉狭窄≥50%定义为阳性,将颈动脉超声结果与冠脉造影结果进行对比分析。结果颈动脉IMT增厚及斑块形成者122例(76.3%),冠脉阳性93例(58.1%)。颈动脉阳性组冠脉阳性89例(73%),通过颈动脉阳性结果推测冠脉阳性,敏感性95.7%,特异性50.7%。颈动脉阳性组与冠脉阳性组分别行危险因素相关性分析,结果提示冠脉造影阳性组年龄、血压、空腹血糖、体重指数(BMI)与阴性组比较有统计学意义(P〈0.05)。颈动脉超声阳性组年龄、血压与阴性组比较有统计学意义(P〈0.05)。结论通过颈动脉超声检测到颈动脉IMT增厚及斑块形成,可为冠状动脉病变提供证据,此方法敏感性较高,特异性较低。且颈动脉IMT增厚及斑块形成与年龄、血压高度相关,冠脉病变与年龄、血压、血糖、BMI值高度相关。
出处 《中国老年学杂志》 CAS CSCD 北大核心 2016年第13期3167-3169,共3页 Chinese Journal of Gerontology
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