利福喷丁与利福平治疗肺结核的疗效与不良反应比较

Comparison the Treatment and Untoward Effect of the Phthisis by Rifapentini and Rifampicin

目的比较利福喷丁与利福平治疗肺结核的疗效与不良反应。方法选择我院2014年7月-2015年7月收治的86例肺结核患者作为研究对象,并随机分为两组,每组43例,对照组采用利福平治疗,实验组给予利福喷丁。详细记录治疗过程中两组患者出现不良反应情况与治疗后临床有效率,并展开对比分析。结果实验组临床治疗总有效率为93.1%,高于对照组的76.7%,差异有统计学意义（P〈0.05）;实验组与对照组不良反应率分别为13.9%、30.2%,两组差异有统计学意义（P〈0.05）。结论利福喷丁较利福平治疗肺结核具有明显临床疗效,且有效降低不良反应率,促进患者恢复健康。

Objective To compared treatment effect and untoward effect of the phthisis by rifapentini and rifampicin. Methods Selected 86 cases of patients with phthisis at our hospital from July 2014 to July 2015 as the object, to randomly divided into two groups, each 43 cases. The control group was treated by rifampicin, the treatment group was treated by rifampicin. To detailed record the untoward effect during the treatment and clinical effective rate of posttreatment, and to comparative analysed them. Results The total effective treatment rate of the treatment group was 93.1%, was higher than the 76.7% of the control, there was statistical significance（P〈0.05）. The untoward effect of the treatment group and control group was 13.9% and 30.2%, there was statistical significance（P〈0.05）. Conclusion That has obvious clinical effects of the phthisis by rifapentini that compared with the rifampicin, and effectively reduce the untoward effect, to improve the pull through of patients.