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卡麦角林治疗泌乳素型垂体瘤的研究进展 被引量:17

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摘要 垂体腺瘤是常见的颅内肿瘤,有研究表明发病率约为4/100 000,在30岁年龄段的发病高达30/100 000~50/100000,而泌乳素型垂体瘤是最常见的功能性垂体瘤,在成人垂体瘤患者中约占了40%~45%[1-3],其主要临床表现为高泌素血症以及压迫症状,包括停经、泌乳、不孕不育、流产、视野缺损、视力下降、头痛等。多巴胺受体激动剂(DA)是治疗泌乳素型垂体瘤的首选方式。卡麦角林(Cabergoline,CAB)是一种新型的长效麦角碱衍生物类多巴胺受体激动剂,其通过抑制泌乳素(PRL)的合成与分泌,能够有效降低泌乳素水平,改善性腺功能,缩小肿瘤体积,
出处 《中国神经精神疾病杂志》 CAS CSCD 北大核心 2016年第5期311-314,共4页 Chinese Journal of Nervous and Mental Diseases
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参考文献29

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二级参考文献19

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