妊娠期高血压619例临床分析

Clinical analysis of 619 cases of pregnant hypertensive disorder

目的比较619例妊娠期高血压疾病患者的一般资料、并发症、妊娠结局和围产儿并发症的情况,为预防不良结局提供依据。方法通过回顾性分析2014年10月至2015年9月在同济大学第一妇婴保健院东院住院分娩的619例妊娠期高血压疾病患者,其中子前期重度190例,子前期轻度153例,妊娠期高血压251例的一般资料、合并症、并发症、妊娠结局、分娩方式和围生儿并发症等临床资料进行统计学分析。结果妊娠期高血压、子前期轻度和子前期重度组,随着病情进展,各组孕龄缩短,剖宫产比例升高,新生儿体重降低(P<0.05),胎儿生长受限、HELLP综合征、肝内胆汁淤积、产后出血等并发症的发生率越高(P<0.01)。结论对于妊娠期高血压疾病,需要更加重视孕妇和胎儿监测,适时终止妊娠,对减少患者出现严重并发症,改善围生儿预后有重要意义。

Objective To analyze the clinical manifestations and outcomes of patients with pregnancy hypertensive disorder.Methods Clinical data of 619 women with hypertensive disorders complicating pregnancy（HDCP） admitted in Tongji University First M aternal and Infant Hospital from October2014 to September 2015 were retrospectively analyzed,including 190 cases of severe preeclampsia,153 cases of hypertensive disorders,251 cases of mild preeclampsia.The general information,complications,outcome,delivery mode and perinatal complications of newborns were documented.Results With the progress of the pregnancy hypertensive disorder,the gestational age was shortened,the proportion of cesarean section increased and neonatal weight decreased（P〈0.05）.The more serious HDCP was,the more fetal growth restriction,HELLP syndrome,intrahepatic cholestasis and postpartum hemorrhage occurred（P〈0.01）.Conclusion For pregnant women with hypertensive disorders,closely monitoring clinical symptoms and timely termination of pregnancy would reduce the incidence of serious complications and improve the prognosis of perinatal infants.