子宫内膜异位症生育指数在人工授精助孕中的预测价值

Predictive value of endometriosis fertility index(EFI)in treatments of intrauterine insemination for endometriosis complicated with infertility

目的总结子宫内膜症生育指数(EFI)与术后不同处理方案临床妊娠率的相关性,探讨EFI评分对子宫内膜异位症(EMS)患者术后最佳治疗方案的指导意义。方法总结我院2010年1月到2015年6月106例EMS不孕患者接受腹腔镜手术术后半年的妊娠状况。患者分为3组:期待组(expectant treatment,ET)、自然周期+人工授精(nature cycle plus IUI,NC+IUI)及促排卵+人工授精(controlled ovarian stimulation plus IUI,COS+IUI),对EFI分值与术后半年的累计妊娠率及治疗方案进行回顾性分析,比较术后半年的妊娠情况。结果在各EFI分值组中,EFI分值6分以上患者半年总计妊娠率显著高于6分以下组(P<0.05),NC+IUI及COH+IUI组的半年累计妊娠率均高于期待自然妊娠组。结论 EFI分值高于6分的EMs不孕患者应积极考虑人工授精助孕技术以提高临床妊娠率。

Objective：To analyze the clinical relevance of endometriosis fertility index（EFI）and clinical pregnancy rate in different treatments for endometriosis（EMS）patients complicated with infertility and to study the predictive value of EFI for EMS. Methods：To analyze the clinical pregnancy outcome of different treatments for 106 patientsby laparoscopyfrom January 2010 to June 2015 in our hospital. The patients were divided into three groups：expectant treatment（ET）,nature cycle plus IUI（NC ＋IUI）and controlled ovarian hyperstimulation plus IUI（COS＋IUI）.To investigatethe relevance of the EFI and factors affecting the pregnancy rates in different treatment cycles. The pregnancy rates of three groups in half year after the operation were compared. Results：Comparing to the group of EFI≤6,the clinical pregnancy rate of EFI〉6 groupwas significantly higher（P〈0.05）. The cumulative pregnancy rates of NC ＋IUI and COS＋IUI group are higher than that of ETgroup respectively. Conclusions：Infertile patients with endometriosis（EFI〉6）should suggested to be assisted reproductive technology treatmentin half year after the laparoscopic treatment. It is also necessary to study further with more samples.