神经调控通路在肠易激综合征内脏高敏感发病机制中作用的研究进展

Advances in Study on Effect of Neural Regulation Pathway on Pathogenesis of Visceral Hypersensitivity in Irritable Bowel Syndrome

肠易激综合征(IBS)是临床最常见的功能性胃肠病之一,影响患者生活质量,给患者日常生活、心理健康带来沉重负担。诸多研究显示内脏高敏感(VHS)是IBS发病的重要病理生理机制之一,神经调控在VHS发生中起关键作用。本文就神经调控通路在IBS VHS发病机制中作用的研究进展作一综述。

Irritable bowel syndrome （IBS） is one of the most common functional gastrointestinal disorders, which impacts on patients＇ quality of life as well as physical and mental health. Studies have shown that visceral hypersensitivity （VHS） is an important pathophysiological factor in the pathogenesis of IBS, and neural regulation plays a key role in the process of VHS. This article reviewed the advances in study on effect of neural regulation pathway on pathogenesis of VHS in IBS.