酒石酸与La^(3+)对草酸钙结晶的影响

Effects of Tartaric Acid and La^(3+) on Calcium Oxalate Crystallization

采用X射线衍射(XRD)、傅立叶红外光谱(FTIR)和扫描电镜(SEM)分析了凝胶体系中混合添加剂酒石酸和La^(3+)对草酸钙(Ca Oxa)晶体生长的影响。研究结果显示,酒石酸可以抑制Ca Oxa晶体的生长、聚集,并诱导二水草酸钙(COD)生成;La^(3+)不仅可诱导COD生成,而且可使一水草酸钙(COM)的形貌发生变化;而酒石酸和La^(3+)的联合作用则不仅增强了对COD的诱导能力,并使COM的聚集程度降低、比表面积减小。酒石酸和La^(3+)的联合疗法对尿石病的预防和治疗有较大的参考价值。

Effects of the mixed additive containing tartaric acid and La3 ＋ on the crystallization of cal- cium oxalate in silica gel were investigated by means of X-ray diffraction （XRD） , Fourier transform infrared （FTIR） spectroscopy and scanning electron microscopy（SEM）. The results indicated that ar- taric acid could inhibit the growth and aggregation of the crystal, and induce the formation of calcium oxalate dehydrate （COD）. La3＋ could also induce the COD formation and affect the morphology of calcium oxalate monohydrate（COM）. While the mixed additive of tartaric acid and La3＋ could not only enhance the ability of inducing the COD formation, but also inhibit the COM aggregation and de- crease the COM surface area. The mixed additive of tartaric acid and La3 ＋ is worthy to be considered for the prevention and treatment of urolithiasis.