胃食管反流病的病理生理新发现被引量：5

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摘要胃食管反流病（GERD）是胃内容物反流入食管导致的以反酸、烧心为主的一组症状。高分辨食管测压、食管腔内阻抗等新检测技术的应用发现，除了下食管括约肌压力下降、一过性下食管括约肌松弛（TLESR）、食管清除功能下降外，上皮间隙增宽，酸袋、反流诱发的黏膜免疫反应等也可影响食管的感知运动功能，诱发症状。此外，近端反流、气体反流、纵行肌收缩、周边和中枢敏感化等多个机制也参与 GERD 症状的产生。我们对 GERD 的病理生理改变概述如下。

作者刘劲松

机构地区华中科技大学同济医学院附属协和医院消化科

出处《临床内科杂志》 CAS 2016年第6期365-367,共3页 Journal of Clinical Internal Medicine

关键词胃食管反流病病理生理

分类号 R57 [医药卫生—消化系统]

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