不同处理方式对妊娠期血小板减少症母婴结局分析

The Analysis of Outcomes of Gestational Thrombocytopenia by Different Processing Methods

目的:探讨不同处理方式对妊娠期血小板减少症母婴结局的影响。方法:收集笔者所在医院2014年1月-2015年6月诊治的中、重度妊娠期血小板减少症孕妇40例,随机分为地塞米松组(A组)及地塞米松联合大剂量丙种球蛋白组(B组),分别对分娩前后血小板计数、分娩情况及新生儿情况进行分析。结果:两组产后血小板计数均高于产前,差异有统计学意义(P<0.05);两组分娩方式比较无统计学意义(P>0.05),A组产后出血率20%,B组产后出血率5%,两组比较差异有统计学意义(P<0.05);产后出血率与处理方式无明显相关性(P>0.05);两组均无新生儿颅内出血及新生儿血小板减少症。结论:地塞米松联合大剂量丙种球蛋白治疗妊娠期血小板减少症可明显减少产后出血等并发症的发生,母婴结局良好。

Objective：To study the outcomes of gestational thrombocytopenia by different processing methods.Method：From January 2014 to June 2015,40 cases of middle and severe gestational thrombocytopenia were collected.They were randomly divided into two groups in the diagnosis and treatment.One was the Dexamethasone group（A group） and the next one was Dexamethasone combination with large dose of Gamma Globulin group（B group）.The platelet count before and after delivery,delivery methods and neonatal situation were analyzed respectively.Result：Postpartum platelet counts in two groups were higher than that in prenatal,the differences were statistically significant（P〈0.05）.The childbirth ways in two groups were no statistical significance（P〉0.05）,postpartum hemorrhage rate was 20% in A group,but in B group,the postpartum hemorrhage rate was 5%,there was statistically significant（P〈0.05）.There was no significant correlation between postpartum haemorrhage rate and treatment（P〉0.05）.In the two groups had no neonatal intracranial hemorrhage and newborn thrombocytopenia.Conclusion：Dexamethasone combines with large dose of gamma globulin in gestational thrombocytopenia can obviously reduce the complications such as postpartum hemorrhage and its outcomes are good.