特布他林预热雾化吸入治疗支气管哮喘急性发作期的效果

Effects of preheated and atomized terbutaline inhalation on treatment of acute attack of bronchial asthma

目的探讨特布他林预热雾化吸入对支气管哮喘急性发作期患者临床症状、病程及肺部通气功能的影响。方法研究对象选取我院收治的支气管哮喘急性发作期患者130例,随机分为对照组(65例)和预热组(65例);均在对症支持治疗基础上,分别给予特布他林常温和预热雾化吸入治疗;比较两组临床治疗总有效率、症状体征改善时间、治疗前后哮喘症状评分和FEV1%、FEV1及PEF水平等。结果预热组临床治疗总有效率显著高于对照组(P<0.05),症状体征改善时间显著短于对照组(P<0.05),治疗后哮喘症状评分显著低于对照组(P<0.05),治疗后FEV1%、FEV1及PEF水平均显著优于对照组(P<0.05)。结论特布他林预热雾化吸入用于支气管哮喘急性发作期患者,可有效缓解呼吸道症状体征,加快病情康复进程,并有助于提高肺功能。

Objective To explore the impacts of preheated and atomized terbutaline inhalation on clinical symptoms, course of disease and lung ventilation function of patients under the acute attack of bronchial asthma. Methods A total of 130 patients under the acute attack of bronchial asthma admitted to our hospital were selected and randomly divided into a control group （n=65） and a preheated terbutaline group （n=65）; the two groups were treated with ambient and preheated and atomized terbutaline inhalation respectively on the basis of symptomatic and supportive treatment; the overall response rate of clinic treatment, the improvement time of symptoms and signs, asthma-symptom scores before and after the treatment, FEVI%, FEV1 and PEF levels in two groups were compared. Results The overall response rate of clinic treatment in the preheated terbutaline group was much higher than that in the control group （P 〈 0.05）; the improvement time of symptoms and signs was significantly shorter than that in the control group （P 〈 0.05）; asthma-symptom scores before and after the treatment were significantly lower than those in the control group （P 〈 0.05）; the FEV1%, FEV1 and PEF levels after the treatment were much superior to those in the control group（P 〈 0.05）. Conchmion Preheated and atomized terbutaline inhalation can effectively relieve respiratory symptoms and signs in patients under acute attack of bronchial asthma, accelerate the rehabilitation process of disease, and help to improve lung function.