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支气管哮喘患者联合检测呼出气一氧化氮及血ECP的临床意义 被引量:2

Clinical Diagnosis Effect of Exhaled Nitric Oxide(FeNO) and Eosinophil Cationic Protein(ECP) Detection in the Bronchial Asthma
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摘要 目的探讨呼出气一氧化氮(FeNO)联合嗜酸粒细胞阳离子蛋白(ECP)诊断支气管哮喘的价值。方法选择60例支气管哮喘患者(观察组),并选择同期60例健康体检者(对照组)。比较两组检测结果。结果观察组FeNO(93.0±11.5)ppb、ECP(290.5±23.6)μg/L明显高于对照组(40.4±6.6)ppb、(58.0±10.8)μg/L,差异有统计学意义(P<0.05)。联合检测FeNO、ECP特异度、灵敏度、阳性预测值、阴性预测值明显优于单项检测结果,差异具有统计学意义(P<0.05)。结论 FeNO、ECP联合检测可有效诊断支气管哮喘。 Objective To study the clinical diagnosis effect of FeNO and ECP detection in the bronchial asthma. Methods 60 cases with bronchial asthma were selected as the observation group, 60 healthy subjects were selected as the control group. The results of two groups were compared. Results Fe NO(93.0±11.5) ppb and ECP(290.5±23.6) μg/L of the observation group were significantly higher than control group(40.4±6.6)ppb,(58.0±10.8) μg/L, with significant difference(P〈0.05). The specificity, sensitivity, positive predictive value, negative predictive value of combined detection FeNO, ECP were significantly better than individual, with significant difference(P〈0.05). Conclusion FeNO and ECP combined detection can effectively diagnose bronchial asthma.
作者 王玲玲
出处 《中国继续医学教育》 2016年第14期28-29,共2页 China Continuing Medical Education
关键词 呼出气一氧化氮 支气管哮喘 嗜酸粒细胞阳离子蛋白 Nitric oxide Bronchial asthma ECP
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