某县735例药品不良反应报告分析

Retrospective Analysis of 735 ADR Case Reports in X Country

目的 探讨某县2015年药品不良反应发生情况及原因,促进临床合理用药。方法 采用回顾性调查方法,统计分析某县2015年收集的ADR报告。结果 735例ADR报告中,2-10岁儿童及60岁以上老人不良反应发生率最高,女性（52.65%）发生率高于男性（47.35%）;给药途径中以静脉滴注发生的ADR最多（78.50%）;引起ADR的药物以抗感染药、抗肿瘤药居首;ADR累及系统或器官,以消化系统、皮肤及其附件、全身性损害最为常见。结论 临床用药时应重视ADR,促进安全合理用药,保证患者用药安全。

Objective The ADR cases reports were analyzed which happened in a county in 2015, which is to promote drug application to be more clinical and rational. Methods Retrospective investigation was used to analyze the ADR cases reports which were collected in 2015. Results The highest rate of ADR happened in children who are aged from two to ten and the old man who are aged beyond sixty. The rate of ADR happened in women（52.65%） was higher than men（47.35%）. The highest rate of ADR happened in Intravenous drip（78.50%） in all of the way to applying drugs. The highest rate of ADR were caused by anti-infective drugs and antitumor drugs. The digestive system, skin and its accessories and the most systemic damage were most likely happened in all of the organ which were involved in ADR. Conclusion ADR should be paid attention to promote drug applying to be rational and safety to ensure patient to be safety when using medicine.