儿科中药及类中药注射剂不良反应报告分析

Analysis of Adverse Drug Reaction Reports of Traditional Chinese Medicine and Traditional Chinese Medicine Injection

目的 分析儿科中药及类中药注射剂不良反应。方法 对我院2013年7月-2014年12月的120例儿科中药及类中药注射剂使用患儿临床资料进行回顾性分析,观察不良反应的表现及用药种类、患儿年龄与不良反应的关系。结果 120例患儿中出现不良反应共23例（19.17%）,细辛脑注射液7例、炎琥宁粉针6例、喜炎平注射剂8例、丹参注射剂2例。1－3岁患儿不良反应的比例较高,为28.00%,随着年龄的增加比例在逐渐的降低。不良反应主要表现为皮肤出现红疹、胃肠不适、恶心呕吐、呼吸急促、寒颤等。结论 在对患者进行中药和类中药注射剂注射后,要时刻观察患者的反应,一旦有不良反应发生,应及时给予有效干预措施。

Objective To discuss adverse drug reaction reports of traditional Chinese medicine and traditional Chinese medicine injection. Methods 120 cases used Chinese herbs and Chinese medicine injections who were selected from July 2013 to December 2014 in our hospital pediatric department were retrospectively analyzed, the performance of adverse reactions, the relationship between the medication type, age of children with adverse reactions. Results A total 23 cases of adverse reactions（19.17%） of 120 cases, asarone injection was 7 cases, Yanhuning powder injection was 6 cases, injection Xiyanping was 8 cases, Salvia injection was 2 cases. The proportion of children 1 to 3 years of adverse reactions was higher, proportion was 28.00%, with age increasing the proportion was gradually reduced. Adverse reactions mainly manifested as skin rashes, gastrointestinal discomfort, nausea, vomiting, shortness of breath, chills and so on. Conclusion In traditional Chinese medicine and patient class traditional Chinese medicine injection after injection, we should always observe the patient, once the adverse reactions, should be timely and effective interventions.