卡前列素氨丁三醇注射液治疗宫缩乏力性产后出血的临床效果

Clinical effect of carboprost tromethamine injection in the treatment of postpartum hemorrhage caused by uterine inertia

目的研究卡前列素氨丁三醇注射液治疗宫缩乏力性产后出血的临床效果。方法选取我院2013年4月~2015年2月收治的83例宫缩乏力性产后出血患者,按随机数字表法将其分为a组和b组,a组常规用催产素治疗,b组在催产素常规治疗同时加用卡前列素氨丁三醇注射液治疗。观察两组止血有效率、药物副作用率、第三产程时间、产后2 h出血量及产后24 h出血量的差异。结果 b组与a组相比,止血有效率更高,药物副作用率更低,第三产程时间更短,产后2 h出血量、产后24 h出血量更少,差异有统计学意义（P〈0.05）。结论卡前列素氨丁三醇注射液治疗宫缩乏力性产后出血的临床效果确切,可有效缩短第三产程时间,减少产后出血量,达到有效止血目的,且用药副作用少,安全性高,值得推广。

Objective To study the clinical effect of carboprost tromethamine injection in the treatment of postpartum hemorrhage caused by uterine inertia.Methods 83 cases of postpartum hemorrhage caused by uterine inertia in our hospital from April 2013 to February 2015 were selected and divided into group a and group b according to random number method.The group a was given regular treatment with oxytocin,the group b was treated with carboprost tromethamine injection on the basis of the oxytocin routine therapy.The hemostasis efficiency,drug side effect rate,the third labor time,the amount of 2 hours of postpartum haemorrhage and 24 hours postpartum haemorrhage in the two groups were observed respectively.Results The hemostasis efficiency in the group b was higher than that in the group a,with significant difference（P〈0.05）.The incidence rate of drug side effect in the group b was lower than that in the group a,with significant difference（P〈0.05）.The third labor time in the group b was shorter than that in the group a,with significant difference（P〈0.05）.The amount of 2 hours of postpartum haemorrhage and 24 hours postpartum haemorrhage in the group b was less than that in the group a,with significant difference（P〈0.05）.Conclusion The effect of carboprost tromethamine injection in the treatment of postpartum hemorrhage caused by uterine inertia is definite,which can effectively shorten the duration time,reduce the incidence rate of postpartum hemorrhage,achieve the purpose of effective hemostasis,and side effect is less,high safety is higher.It is worth promoting.