卡泊芬净联合克林霉素治疗重症肺孢子菌肺炎的临床观察

Clinical Observation on Caspofungin and Clindamycin in the Treatment of Severe Pneumocystis Pneumonia

目的探讨卡泊芬净联合克林霉素治疗重症肺孢子菌肺炎的临床效果。方法将82例重症肺孢子菌肺炎患者分为两组,治疗组采取卡泊芬净联合克林霉素治疗,对照组采取卡泊芬净治疗,对比2组疗效。结果治疗组治疗总有效率95.1%,高于对照组的75.6%(P<0.05)。结论卡泊芬净联合克林霉素治疗重症肺孢子菌肺炎的效果理想。

Objective To investigate clinical effect of caspofungin in combination with clindamycin in the treatment of severe Pneumocystis pneumonia.Methods 82 cases of severe Pneumocystis pneumonia patients divided into two groups. Treatment group taking caspofungin combined with clindamycin treatment, the control group was treated with caspofungin. The curative effects were compared between two groups.Results Treatment group of total rate was 95.1%,was significantly higher than that of the control group of 75.6%（P〈0.05）.Conclusion Combination of caspofungin and clindamycin in treatment of severe Pneumocystis pneumonia have ideal effect.