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原发性中枢神经系统淋巴瘤MRI表现与病理对照分析 被引量:4

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摘要 分析28例我院经病理证实的PCNSL患者MRI特征及病理基础,所有患者均行MR平扫、增强扫描、病理切片及免疫化学检测。单发21例(75.0%),多发7例(25.0%),共有病灶42个;单发肿瘤均匀强化35个(83.3%),不均匀强化4个(9.5%),周围无明显水肿6个(14.3%)、轻度20个(47.6%)、中度10个(23.8%)、重度6个(14.3%),病灶轻度占位18个(42.9%),重度5个(11.9%)。T1WI呈稍低信号31个(73.8%)、等信号7个(16.7%)、稍高信号3个(7.1%)、高信号1个(2.4%);T2WI呈稍低信号11个(26.2%)、等信号5个(11.9%)、稍高信号24个(57.1%)、高信号2个(4.8%);35例(83.3%)肿瘤细胞弥漫密集片状分布于血管周围,42个瘤组织均表达CD45、CD20、CD79a,均不表达GFAP、S-100、EMA和CKp CD45,提示为弥漫大B细胞淋巴瘤,少见间质成分、出血、大片坏死及钙化现象,32例(76.2%)肿瘤组织网状纤维丰富。PCNSL患者的MRI表现具有特征性,与PCNSL病理基础密切联系。
出处 《现代诊断与治疗》 CAS 2016年第10期1869-1870,共2页 Modern Diagnosis and Treatment
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