急性高脂血症性胰腺炎与急性胆源性胰腺炎的临床特征比较

Comparison of clinical features of hyperlipide acute pancreatitis and acute biliary pancreatitis

目的比较高脂血症性急性胰腺炎(hyperlipide acute pancreatitis,HLAP)与急性胆源性胰腺炎(acute biliary pancreatitis,ABP)的临床特征的异同点。方法选取诊断明确的HLAP患者38例,ABP患者185例,比较两种急性胰腺炎(acute pancreatitis,AP)的一般临床特征、严重度、生化功能和血脂以及C反应蛋白(CRP)、改良CT严重度指数(modified CT severity index,MCTSI)的差别。结果与ABP比较,HLAP发病年龄较低,男性居多,肥胖体型多见,多数伴有糖尿病和脂肪肝;临床腹痛缓解时间长,并发症发生率高;易发展为重度,高甘油三酯血症多见,胰腺坏死多见。CRP和MCTSI在检测HLAP胰腺坏死发生上有应用价值。结论与ABP比较,HLAP临床特征有不同之处,且病情较重,易发生胰腺坏死等,应引起高度重视。

Objective To investigate and compare the clinical features of hyperlipide acute pancreatitis （ HLAP ） and acute biliary pancreatitis （ABP）.Methods According to the diagnosis and therapy guideline of China ,we included 238 patients with HLAP or ABP and then compared the differences in clinical features ,severity,biochemistry and blood lipid as well as CRP and MCTSI between the two types of disease .Results Compared with ABP ,HLAP patients were younger ,male in the majority and most with diabetes or fat-ty liver and the abdominal pain relief time was longer and the complication rate was higher .CRP and MCTSI were valued to detect pan-creatic necrosis .Conclusion The clinical characteristics of HLAP were different from that of ABP .The condition of HLAP is more se-rious.Higher degree of attention has to be paid to HLAP patients ..