摘要
目的观察窄波UVB联合伐昔洛韦治疗带状疱疹及神经痛的疗效。方法选择2013年1月-2015年2月收治的158例带状疱疹患者为研究对象,采用随机数字表法分为观察组和对照组各79例,对照组给予口服伐昔洛韦片治疗,观察组采用窄波UVB联合伐昔洛韦治疗。两组疗程均为10d,比较两组治疗效果、临床症状改善情况、后遗神经痛的发生率。结果观察组总有效率97.47%明显高于对照组86.08%(x2=6.789,P〈0.05);水疱停止出现时间、结痂时间、皮损恢复时间均短于对照组(t=6.759~8.260,P〈0.05);疼痛缓解时间、疼痛消失时间明显短于对照组(拄5.886~10.868,P〈0.05),随访1个月,观察组后遗神经痛发生率(7.59%)明显低于对照组(21.52%)(x2=6.157,P〈O.05)。结论窄波UVB联合伐昔洛韦治疗有助于缓解患者临床症状,减轻疼痛程度,预防后遗神经痛发生,提高治疗效果。
Objective To study effect of NB-UVB combined with valacyclovir in treatment of herpes zoster and neu- ralgia. Methods 158 cases patients with herpes zoster from January 2013 to February 2015 were divided into observa- tion group and control group,control group was given valacyclovir therapy,the observation group was given NB-UVB combined with valacyclovir therapy,then therapy effect,clinical symptoms,neuralgia were compared between two groups. Results Observation group's effective rate was 97.47%, significantly higher than the control group 86.08%(x2=6.789, P〈0.05); Blister stop time, scab over time, skin recovery time were significantly shorter than the control group(t=6.759- 8.260, P〈0.05); Pain relief time,pain disappeared time were significantly shorter than the control group(t=5.886-10.868, P〈0.05); Followed up for 1 month,the observation group neuralgia rate was 7.59%, significantly lower than the control group 21.52%(x2=6.157, P〈0.05). Conclusion NB-UVB combined with valacyclovir therapy help to ease clinical symp- toms, relieve pain, and prevent the heritage neuralgia, then improve therapy effect.
出处
《中国现代医生》
2016年第16期75-77,共3页
China Modern Doctor