鸦胆子仁浸剂治疗CINⅠ伴人乳头瘤病毒感染的临床疗效

The Clinical Observation of Brucea Javanica Treatment of CINⅠ Caused by the Infection of High-riskHPV

目的:探讨鸦胆子仁浸剂治疗CINⅠ伴人乳头瘤病毒(HPV)感染的临床疗效。方法:选取本院妇科门诊CINⅠ伴HPV感染86例,将患者随机分为两组,治疗组与空白对照组,每组各43例。治疗组应用鸦胆子仁浸剂,空白对照组不使用任何药物,比较两组患者治疗HPV情况及CINⅠ消退情况。结果:用药3个疗程后,治疗组治疗HPV有效率60.5%,空白对照组2.3%,CINⅠ消退有效率分别为58.0%和2.3%,治疗组明显优于空白对照组,两组比较差异均有统计学意义(P<0.05)。结论:鸦胆子仁浸剂治疗CINⅠ伴HPV感染安全、有效。

Objective：To discuss clinical curative effect of Brucea javanica treatment of CINⅠ caused by the infection of high-risk HPV.Method：86 cases of CINⅠ with human papilloma virus infection in outpatient service department of gynaecology were selected.Patients were randomly divided into two groups,treatment group and blank control group,43 cases in each group.The treatment group was given Brucea javanica,blank control group did not use any drugs.The treatment of HPV and CINⅠ regression of two groups were compared.Result：After 3 courses treatment of HPV,the effective rate of treatment group was 60.5%,and blank control group was 2.3%,for CINⅠ efficient rate of two groups were respectively 58.0% and 2.3%,treatment group of those were better than blank control group,the differences were statistically significant（P〈0.05）.Conclusion：Infusion of Brucea javanica in the treatment of CINⅠ with human papilloma virus infection is safe and effective.