期刊文献+

中药自拟方治疗艾滋病患者转氨酶升高 被引量:1

下载PDF
导出
摘要 背景:艾滋病患者体质差,西药中抗病毒药物不良反应大,可引起肝损伤甚至肝衰竭而危及生命。目的:探讨中药治疗艾滋病抗逆转录病毒(HAART)治疗引起肝损伤转氨酶升高的效果。方法:用中药自拟方茵柴护肝汤加减艾滋病抗病毒西药治疗后转氨酶升高者35例,观察治疗前后临床症状、肝功能、临床效果的变化。结果与结论:临床总有效率80%。治疗后,临床症状明显改善,肝功能如谷丙转氨酶、谷草转氨酶、血清总胆红素和直接胆红素亦均有明显改善(P〈0.01或P〈0.05);CD4淋巴细胞无明显变化(P〉0.05)。提示中药自拟方茵柴护肝汤对艾滋病抗病毒西药治疗引起的转氨酶升高有保肝降酶作用,对抑制病毒无影响,可改善临床症状,提高生存质量。
出处 《中国组织工程研究》 CAS 北大核心 2016年第B05期207-208,共2页 Chinese Journal of Tissue Engineering Research
  • 相关文献

参考文献3

二级参考文献20

  • 1王宪龄,李连珍,牛万强.柴胡与黄芩不同剂量比例配伍对扑热息痛所致小鼠急性肝损伤的保护作用[J].河南中医,2004,24(8):15-17. 被引量:19
  • 2杨错,刘玉兰,张红梅.肝细胞损伤机制及防治药物研究进展[J].实用药物与临床,2005,8(6):44-46. 被引量:16
  • 3王宪龄,李伟,刘方洲,张影,李连珍.柴胡黄芩配伍对CCl_4所致小鼠急性肝损伤的研究[J].中药药理与临床,2005,21(6):11-13. 被引量:19
  • 4U. S. Public Health Service(USPHS) and Infectious Disease Society of America( IDSA). 2001 USPHA/IDSA guidelines for the prevention of opportunistic infected with human immunodeficiency virus [ J ].MMWR,2001,1 - 68.
  • 5Burman W, El-Sadr WE, Matts J, et al. Continued low rates of Mycobacterium avium complex and bacterial pneumonia despite withdrawal of azithromycin prophylaxis among patients with CD4^+ cell rebound[A]. Program and abstracts of the 9th Conference on Retroviruses and Opportunictic Infections [ C]. Seattle, Washington, February 24 -28,2002,631.
  • 6Yangco BG, Von Bargen JC, Moorman AC, et al. Can PCP prophylaxis be safely discontinued among clinically improving HIV patients[ C] ?[ Abstract I - 262 ]. 38th ICAAC, San Diego, CA, 1998.
  • 7Anglaret X, Chene G, Attia A, et al Early chemotherapy with trimethoprin-sulphamethoxazole for HIV-1 infected adults in Abidjan,Cote d' Ivoire: a randomised control trial[J ]. Lancet, 1999,353:1463-1468.
  • 8Wiktor SZ Morokro MS, Grant AD, et al. Efficacy of trimethoprin-sulphamethoxazole prophylaxis to decrease morbidity and mortality in HIV-linfected patients with tuberculosis in Adidjan, Cote d' Ivoire: a randomised control trial [J ]. Lancetl, 999,353:1469 - 1474.
  • 9Mellors JW, Munoz A, Giogi TV. et al. Plasm viral load and CD4^+ lymphacytes as prognostic markers of HIV-1 infection[J ]. Ann Intern Med,1997,126:946- 954.
  • 10Tansuphasawedikul S, Amornkul PN, Tanchanpong C, et al. Clinical presentation of hospitalized adult patients with HIV infection and AIDS in Bangkok,Thailand[J] .Acquir Immune Defic Syndr, 1999,21(4) :326 - 332.

共引文献100

同被引文献3

引证文献1

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部