摘要
目的 探讨急性心肌梗死（acute myocardial infarction,AMI）患者红细胞分布宽度（red blood cell distribution width,RDW）变化及其与Gensini积分的关系,评价RDW对严重冠状动脉病变的预测价值。方法 AMI患者135例为AMI组,冠心病非AMI患者118例为对照组,比较2组临床资料及冠状动脉病变程度,采用Gensini积分评价冠状动脉病变严重程度,分析其与RDW的关系;应用多因素logistic分析评估严重冠状动脉病变（Gensini积分〉20）的独立预测因素。结果 AMI组患者RDW[（13.19±1.23）%]高于对照组[（12.56±0.99）%],2组比较差异有统计学意义（P〈0.05）;RDW与Gensini积分呈正相关（r=0.493,P=0.000）;以Gensini积分为因变量,多因素logistic分析显示,RDW是严重冠状动脉病变的独立危险因素（OR=2.120,95%CI：1.139~3.950,P=0.005）。结论 AMI患者RDW水平升高,RDW可作为冠状动脉严重病变的独立预测因素。
Objective To evaluate the value of red blood cell distribution width （RDW） to the prediction of severe coronary artery lesions by exploring the changes of RDW and its relationship with Gensini score in the patients with acute myocardial infarction （AMI）. Methods The clinical data of and severity of coronary artery lesions were compared by Gensini score between 135 patients with AMI （AMI group） and 118 patients with coronary heart disease （CHD） and no AMI patients （control group） to analyze its relationship with RDW. Multivariahle logistic analysis evaluation was adopted to evaluate the independent factors of severe coronary lesions （Gensini score 〉 20）. Results The RDW value was significantly higher in AMI group （（13.19± 23）%） than that in control group （（12. 56±0.99）%） （P〈0.05）. RDW was positively correlated with Gensini score （r=0. 493, P：0. 000）. Taking Gensini score as a dependent variable, multivariable logistic analysis showed that RDW was independently correlated with severe coronary artery lesions （OR- 2. 120, 95%CI.. 1. 139 to 3. 950, P=0. 005）. Conclusion RDW is elevated in AMI patients, and it can serve as an independent predictor for severe coronary artery lesions.
出处
《中华实用诊断与治疗杂志》
2016年第7期666-668,共3页
Journal of Chinese Practical Diagnosis and Therapy
基金
国家自然科学基金(81170307)
