氨茶碱与多索茶碱治疗支气管哮喘疗效对比

The discuss of the clinical effect of aminophylline and doxofylline in the treatment of patients with bronchial asthma

目的:探讨氨茶碱与多索茶碱在支气管哮喘患者治疗中的临床效果对比。方法:选取我院收治的90例支气管哮喘患者,随机分为对照组与观察组,每组45例,对照组采用氨茶碱进行治疗,观察组采用多索茶碱进行治疗,比较两组的临床疗效。结果:观察组与对照组的治疗总有效率分别为93.3%和77.8%,两组比较差异显著(P<0.05);观察组临床症状的消失时间明显短于对照组(P<0.05);两组患者治疗后的肺功能指标改善情况相比,观察组明显优于对照组;治疗后,观察组与对照组出现不良反应的发生率分别为6.7%和17.8%,两组比较差异显著(P<0.05)。结论:在支气管哮喘患者的治疗中,氨茶碱与多索茶碱的临床效果相比,多索茶碱的临床疗效明显较好,能够明显改善患者的肺功能,用药安全性高,具有推广的价值。

Objective： To study the clinical effect of aminophylline and doxofylline in the treatment of patients with bronchial asthma. Method： In our hospital 90 cases of bronchial asthma patients were selected and randomly assigned into control group and observation group,with 45 cases in each group. The control group were treated with aminophylline,while observation group with doxofylline. The clinical efficacy was compared between the two groups. Result： The total effective rate of observation group and control group were 93. 3% and 77. 8%,respectively. The difference was significant（ P〈0. 05）; and the disappearance time of clinical symptoms in observation group was significantly shorter than that in control group（ P〈0. 05）. The effect in observation group was significantly better than that in control group. The incidence of adverse reactions in observation group and control group were 6. 7% and 17. 8%,and the difference was significant（ P〈0. 05）. Conclusion： In the treatment of patients with bronchial asthma,compared with the clinical effects of aminophylline,the clinical curative effect of doxofylline is significantly better. It can obviously improve the lung function of patients,and medication safety is high,which is valuable for wide promotion.