泪道插管术与干眼症发生的相关性研究

The clinic research of the nasolacrimal duct intubation and xerophthalmia

目的:研究泪道插管术与干眼症的发生关系,探讨泪道插管术与干眼症之间的临床意义。方法:对同期治疗的283例泪道阻塞疾病患者随机分组,进行前瞻性研究,其中142例179只眼行泪道探通插管术,141例165只眼行非泪道插管术治疗。根据其不同性别、不同年龄段及职业中干眼症的发生情况,并进行统计学分析。结果:同期治疗的泪道阻塞疾病患者中142例179只眼行泪道探通插管术,54只眼术后发生干眼症,发生率为30.1%。其余141例165只眼干眼病发生44只,发生率为26.6%,χ2检验显示泪道插管术与干眼症的患病率无明显统计学意义。多因素回归分析显示干眼症的发生与年龄、性别存在密切的关系,高龄、女性患此病的发生率高。结论:泪道插管术并不是干眼症发生的危险因素,泪道阻塞和干眼症二者可以同时发病,对于溢泪的泪道阻塞患者,要进行干眼症的常规检查,然后再进行泪道插管术治疗,以免术后加重干眼。

Objective： To study the relationship of the nasolacrimal duct intubation and xerophthalmia; and to explore the clinical significance between them. Methods： 283 patients with lacrimal duct disease who were randomly divided into two groups were studied respectively,of which 142 cases（ 179eyes） were cured by means of the nasolacrimal duct intubation,whereas the other 141 cases（ 165eyes） were managed by other means. The factors of gender,ages and occupations were analyzed. Results： 54 eyes occurred xerophthalmia among 142 cases（ 179eyes）compared with 44 eyes in 141 cases（ 165eyes）,and their incidences were 30. 1% and 26. 6% respectively. Theχ2test shows no significance. Logistic analysis reveals that xerophthalmia correlates with age and gender. The aged and female patients are susceptible to this disease. Conclusion： The nasolacrimal duct intubation is not the risk factor for xerophthalmia. Lacrimal duct obstruction may coexist with xerophthalmia in the same patient. The routine examination is very necessary for patients of lacrimal duct obstruction. After that the nasolacrimal duct intubation can be performed so as not to aggravate the symptoms of xerophthalmia followed by the nasolacrimal duct intubation.