脑梗死急性期患者溶栓治疗过程中的安全隐患与对策

Research on the potential safety hazard and protection measures for acute cerebral infarction patients during the thrombolytic therapy

目的针对脑梗死急性期患者在溶栓治疗过程中出现的安全隐患进行探讨总结,实施相应的对策并探究分析其临床效果。方法选择86例脑梗死急性期患者作为本次观察对象,均为2013年10月—2015年10月在该院进行溶栓治疗的患者,将2013年10月—2014年10月的43例患者作为对策实施前,2014年10月—2015年10月的43例患者作为对策实施后,总结实施前出现的安全隐患并针对其给予相应的对策,对比分析对策实施前后的安全隐患发生情况、患者的生活质量及治疗疗效情况。结果实施前安全隐患的总发生率为46.51%,明显高于实施后安全隐患的总发生率13.95%,其差异具有统计学意义(P<0.05);实施后43例患者各方面的生活质量评分较实施前相比均有所提高,其差异具有统计学意义(P<0.05);对策实施后患者溶栓治疗的成功率(93.02%)明显高于实施前的(62.79%)其差异具有统计学意义(P<0.05)。结论脑梗死急性期患者在溶栓治疗过程中存在的安全隐患较多,给予一定的对策可以减少其发生,建议广泛应用。

Objective To conclude the potential safety hazard for acute cerebral infarction （ACI） patients during the throm- bolytic therapy and explore its corresponding measures and clinical effect. Methods 86 ACI patients of receiving the throm- bolytic therapy from January 2013 to October 2014 in our hospital were selected. From January 2013 to January 2015, the countermeasure was not applied; from October 2014 to October 2015, the countermeasure was applied. The potential safety hazard and corresponding measures were concluded; the incidence rate of potential safety hazard, the patient＇s life quality and curative effect before and after intervention was comapred. Result After intervention, the overall incidence rate of po- tential safety hazard （13.95%） was signfieantly lower than before （46.51%） （P〈0.05）; after intervention, the evaluation score of life quality was signficantly higher than before （P〈0.05）; after intervention, the success rate of thromboltic therapy （93.02%） was signficantly higher than before （62.79%） （P〈0.05）. Conclusion During the thrombolytic therapy, ACI patients are easy to have the potential safety hazards. The corresponding measures can reduce the incidence rate of potentional safe- ty hazards. It is worthy of extensive application.