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对比剂肾病早期诊断生物标志物的研究进展 被引量：2

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摘要 随着放射诊断及冠状动脉介入诊疗技术的发展、人类预期寿命的延长，使用血管内对比剂的人群逐年增加。尽管上述人群中出现肾功能不全的患者不足1％，但在具有慢性肾病、糖尿病、使用。肾毒性药物等危险因素的患者中，使用对比剂后对比剂肾病（contrast induced nephropathy，CIN）的发生率高达25％，且有10％～12％最终需要肾替代治疗。
作者 蔡莹 赵威 高炜
机构地区 北京大学第三医院心内科卫生部心血管分子生物学与调节肽重点实验室及分子心血管学教育部重点实验室
出处 《中国介入心脏病学杂志》 2016年第6期343-346,共4页 Chinese Journal of Interventional Cardiology
关键词 冠状动脉造影 生物标志物 对比剂肾病
分类号 R816.2 [医药卫生—放射医学]
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参考文献35

  • 1Shaker OG, E1-Shehaby A, E1-Khatib M. Early diagnostic markers for contrast nephropathy in patients undergoing coronary angiography. Angiolngy, 2010,61 (8) :731-736.
  • 2Tasanarong A, Hutayanon P, Piyayotai D. Urinary Neutrophil Gelatinase-Assoeiated Lipocalin predicts the severity of contrast- induced acute kidney injury in chronic kidney disease patients undergoing elective coronary procedures. BMC Nephrol, 2013, 14,270.
  • 3Seeliger E, Sendeski M, Rihal CS, et al. Contrast-induced kidney injury : mechanisms, risk factors, and prevention. Eur Heart J, 2012, 33 (16) :2007-2015.
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  • 9MeCullough PA, Williams FJ, Stivers DN, et al. Neutrophil gelatinase-associated lipocalin: a novel marker of contrast nephropathy risk. Am J Nephrol, 2012, 35(6) :509-514.
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二级参考文献12

  • 1Nguyen MT,Devarajan P.Biomarkers for the early detection of acute kidney injury[J].Pediatr Nephrol,2008,23:2151-2157.
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  • 8Malyszko J,Bachorzewska-Gajewska H,Poniatowski B,et al.Urinary and serum biomarkers after cardiac catheterization in diabetic patients with stable angina and without severe chronic kidney disease[J].Ren Fail,2009,31:910-919.
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共引文献16

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二级引证文献10

中国介入心脏病学杂志
2016年 第6期

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