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PET-MRI与MR、CTI对脑胶质瘤精确放疗靶区影响的研究 被引量:1

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摘要 目的探讨PET-MRI和MRI、CT图像对脑胶质瘤放疗靶区确定的差异。方法选取5例经病理证实为胶质瘤患者的术前PET-MRI和MRI、CT图像及对5例经MRI诊断复发的胶质瘤患者的PET-MRI和MRI、CT图像,分别由我科医师在三种图像资料上确定放疗靶区,比较三者差异。结果 5例胶质瘤患者术前影像检查确定的GTVCT与GTVMRI中,GTVMRI比GTVCT平均增大为15.8%,GTVPETMR与GTVMRI重合度最大为75.0%,最小为53.5%。5例MRI诊断复发胶质瘤患者中,3例表现为11CMET高摄取,PET报告为复发,3例病理证实为复发。另1处呈轻度摄取,PET考虑放射性损伤,病理学检查证实为放射性脑病。余1例显像阴性,病理证实确无复发。5例患者MRI共报告6处复发,且均为异常强化区,病理检查4处复发,1处病理学检查证实为放射性脑病,1处病理证实确无复发。结论 PET-MRI融合技术可以更精确地勾画胶质瘤病灶的边界,更准确地鉴别手术及放疗后的局部纤维化或瘢痕组织与肿瘤复发。
出处 《齐齐哈尔医学院学报》 2016年第12期1535-1536,共2页 Journal of Qiqihar Medical University
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