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Understanding the pathogenic evolution of Zika virus 被引量:1

Understanding the pathogenic evolution of Zika virus
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摘要 Unlike the previous circulating strains that were not associ- ated with significant human pathology, recent circulating Zika virus (ZIKV) strains isolated during the 2015-2016 Brazilian Outbreak are highly suspected to cause neuropa- thology, including disorders of fetal brain development and Guillain-Barr6 syndrome (Broutet et al., 2016). Studies have revealed that recent ZIKV strains can be spread through maternal-fetal (Calvet et al., 2016) and sexual (Hills et al., 2016) transmission, in addition to the traditional route of infection via mosquitoes. Unlike the previous circulating strains that were not associated with significant human pathology,recent circulating Zika virus(ZIKV)strains isolated during the 2015–2016Brazilian Outbreak are highly suspected to cause neuropathology,including disorders of fetal brain development and Guillain-Barrésyndrome(Broutet et al.,2016).Studies have revealed that recent ZIKV strains can be spread through maternal-fetal(Calvet et al.,2016)and sexual(Hills et al.,2016)transmission,in addition to the traditional
作者 Xiao-Feng Qin
出处 《Science China(Life Sciences)》 SCIE CAS CSCD 2016年第7期737-739,共3页 中国科学(生命科学英文版)
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  • 1Broutet, N., Krauer, F., Riesen, M., Khalakdina, A., Almiron, M., Aldighi- eri, S., Espinal, M., Low, N., and Dye, C. (2016) Zika Virus as a cause of neurologic disorders. N Engl J Med 374, 1506-1509.
  • 2Calvet, G., Aguiar, R.S., Melo, A.S., Sampaio, S.A., de Filippis, I., Fabri, A., Araujo, E.S., de Sequeira, P.C., de Mendonqa, M.C., de Oliveira,L., Tschoeke, D.A., Schrago, C.G., Thompson, F.L., Brasil, P., Dos Santos, F.B., Nogueira, R.M, Tanuri, A., and de FilippJs, A.M. (2016). Detection and sequencing of Zika virus from amniotic fluid of fetuses with microcephaly in Brazil: a case study. Lancet Infect Dis doi: 10.1016/S 1473-3099( 16)00095-5.
  • 3Hills, S.L., Russell, K., Hennessey, M., Williams, C., Oster, A.M., Fischer, M., and Mead, P. (2016) Transmission of Zika Virus through sexual contact with travelers to areas of ongoing transmission - Continental United States, 201@ MMWR Morb Mortal Wkly Rep 65,215-216.
  • 4Wang, L, Valderramos, S. G., Wu, A., Ouyang, S., Li, C., Brasil, P., Bonaldo, M., Coates, T., Nielsen-Saines, K., Jiang, T., Aliyari, R., and Cheng, G. (2016). From mosquitos to humans: genetic evolution of Zika Virus. Cell Host Microbe doi: 10.1016/j.chom.2016.04.006.
  • 5Lanciotti, R.S., and Lambert, A.J. (2016). Phylogenetic analysis of chikungunya virus strains circulating in the western hemisphere. Am J Trop Med Hyg 94, 800-803.

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