多主题团体对改善精神分裂症患者症状及社会功能的研究

The study of improving the symptoms and social function of schizophrenic in multi-thematic group therapy

目的探讨团体治疗前后不同研究组PANSS评分在不同时间点上及组间的差异,以考察多主题组是否比其他单一主题组具有更好的近期和远期疗效。方法将300例青年期精神分裂症恢复期患者随机分成4个实验组(多主题组60人、情绪管理组60人、自我探索组60人、人际关系组)和对照组(60人),4个实验组在保持与对照组一样药物治疗的前提下,各组实施不同方式的团体治疗方案,在治疗前后及治疗后3、6个月采用阳性与阴性症状量表(Positive and Negative Syndrome Scale,PANSS)和个体和社会功能量表(PSP)对5个组进行评定。对所得数据进行描述性统计分析、方差分析。结果 4个实验组PANSS和PSP的总分在治疗结束、治疗后3个月、治疗后6个月上与治疗前均存在有统计学意义(P<0.01);而对照组的PANSS和PSP总分在这些时间点上,除了治疗前与治疗后3个月差异有统计学意义(P>0.05)外,差异不具有统计学意义。随后的事后检验显示多主题组的PANSS总分在4个时间点的两两比较,除了治疗结束与治疗后3个月相比无统计学意义外,其他均有统计学意义。而PSP总分在4个测试时间点的两两比较,除了4组实验组治疗前和治疗结束有显著差异外,其他差异均有统计学意义。组间差异分析显示,多主题组在PANSS、PSP的总分在各个时间上均高于自我探索组、情绪管理组、人际关系组及对照组,其中治疗后3个月多主题组与自我探索组在PANSS上差异有统计学意义,治疗后6个月多主题组与其他组在PANSS总分上、多主题组与自我探索组在PSP总分上差异有统计学意义(P<0.01)。结论多主题组在改善精神分裂症患者的症状和社会功能方面比单一主题的自我探索组、情绪管理组及人际关系组无论是近期效果还是远期效果上均具有明显的优势。

Objective To study the difference of PANSS scores at different time points before and after the group thera- py. To export whether the multi-thematic group has a better short-term and long-term efficacy than other single group pro- gram group topics. Methods Three hundred cases of adult schizophrenia convalescent patients were randomLy divided into four experimental groups （multi-thematic group of 60 people, emotional management group of 60 people, self-exploration group of 60 people,relationships group） and control group （60）, The four experimental groups accept the drug therapy a- lone as the same as the control group. Various groups take different ways of group therapy program,The five groups were e- valuated before and after treatment and after 3 months of treatment, after 6 months of treatment by the Positive and Negative Syndrome Scale （Positive and Negative Syndrome Scale, PANSS） and individual and social function scale （PSP） for the five groups were evaluated. The data were descriptive statistical analysis, analysis of variance. Results There are signifi- cantly different in 4 experimental groups by PSP PANSS total score at the end of treatment, after treatment three months, af- ter treatment six months. While the control group was significant difference between before treatment and after 3 months of treatment （P 〉 0. 05 ） by PSP and PANSS, others was not significant. The pairwise comparison test four time points by PSP, in addition to 4 experimental groups before and after treatment were significantly different, the other were not significant. Multi-topic group total score of PANSS, PSP was higher than self-exploration group, anger management groups, interpersonal relationships and control groups at each time. After 3 months of treatment in which the multi-thematic groups and self-explo- ration group were significant difference on the PANSS. After 6 months of treatment in which the multi-thematic groups and other group were significant difference on the PANSS. After 6 months of treatment in which the multi-thematic groups and self-exploration group differences in the PSP. Conclusion Multi-topic group in improving symptoms and social function in patients with schizophrenia than a single theme of self-exploration group, emotion management and interpersonal group either group had obvious advantages on both short-term effect and long-term effects.