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调节性T细胞促进胃癌发生的研究进展 被引量:5

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摘要 胃癌(GC)发病因素和机制复杂,GC和机体免疫系统中的调节性T细胞(Treg)密切相关。Treg是一群具有免疫抑制功能的细胞,在维持机体免疫稳态中有重要调节功能,Treg在肿瘤中的作用已成为研究热点。GC患者体内Treg上调,从而抑制机体的抗肿瘤免疫。因此,Treg参与GC的发生发展过程,针对Treg的免疫疗法对于治疗GC具有广阔前景。本文着重就Treg促进GC的作用以及Treg作用机制的研究进展进行综述。
出处 《细胞与分子免疫学杂志》 CAS CSCD 北大核心 2016年第8期1140-1143,共4页 Chinese Journal of Cellular and Molecular Immunology
基金 国家中医临床研究基地业务建设科研专项(JDZX2012089)
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