需左旋甲状腺素治疗桥本甲状腺炎的超声特征分析

HASHIMOTO'S THYROIDITIS REQUIRING TREATMENT WITH LEVOTHYROXINE:ANALYSIS OF ITS SONOGRAPHIC FEATURES

目的探讨需应用左旋甲状腺素(优甲乐)治疗的桥本甲状腺炎(HT)病人甲状腺超声特征。方法HT病人126例,其中服用优甲乐治疗半年以上者65例,未用优甲乐治疗病人61例。应用超声检查两组病人甲状腺回声特征,化学发光法检查甲状腺功能。比较两组不同甲状腺功能分级间超声特征的差异。结果使用优甲乐组不同甲状腺功能分级间甲状腺包膜特征和血流多普勒特征差异有显著性(Hc=7.998、26.888,P<0.05),未用优甲乐组不同甲状腺功能分级间甲状腺回声强度、血流多普勒特征差异有显著意义(Hc=9.450、35.041,P<0.01)。结论甲状腺超声特征可反映HT的进展程度,为HT的优甲乐治疗提供可靠的评价信息。

Objective To investigate the ultrasonic features of Hashimoto＇s thyroiditis（HT）that needed to be treated with Levothyroxinet. Methods A total of 126 HT patients were recruited,of whom,65 had been treated with oral Levothyroxine for more than half a year,and the other 61 were not treated with this medicine prior.Using ultrasonography to detect the echo features of the thyroid in patients of the two groups and employing chemiluminescence to determine thyroid function. Results Ultrasonography revealed that in patients treated with Levothyroxine,in different thyroid function classifications,the differences in the characteristics of thyroid capsule and Doppler blood flow were significant（Hc=7.998,26.888;P〈0.01）,and those who were not treated with Levothyroxine,in different thyroid function classifications,the differences in thyroid echo intensity and Doppler blood flow were significant（Hc=9.450,35.041;P〈0.05）. Conclusion Ultrasound features of thyroid can reflect the progression extent of Hashimoto＇s thyroiditis,which provides reliable information for assessment of Levothyroxine in treating the disease.